Vertex US Distribution Posted September 8, 2026

Epidemiology Forecasting Director

5000, United States Full time
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Vertex US Distribution is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

The Epidemiology Forecasting team develops patient population forecasts used to inform commercial opportunity and forecasting, clinical trial planning, long-range planning, regulatory filings, and external communications.

The Director, Epidemiology Forecasting is responsible for supporting programs through the execution of strategic plans to obtain scientifically rigorous global estimates of the incidence, prevalence, and population size for diseases being investigated for treatment. The role will report to the Senior Director, Epidemiology Forecasting.

Key Responsibilities:

Lead systematic literature reviews and database/disease registry studies and contribute to primary observational studies to ensure the development of scientifically rigorous estimates of disease incidence, prevalence, and population size

Generate quality global estimates of disease incidence, prevalence, and population size for disease areas

Collaborate with cross-functional partners in commercial, business development, medical, clinical, regulatory, corporate communications, and other functions

Support internal processes and participate in cross-functional teams to achieve alignment of strategic plans and recommended approach/level of investment at each stage of development to ensure quality epi deliverables meet the needs of the organization

Develop innovative solutions to ensure the organization has the relevant epidemiologic information, particularly where existing evidence is sparse

Key Requirements:

PhD/DSc/DrPH in Epidemiology or related discipline with at least 10 years of industry experience in the biopharmaceutical or consulting environment or MPH/MSc with at least 12 years’ experience

Directly relevant experience in: Developing disease population size estimates

Executing research to generate scientifically rigorous epidemiology estimates, including systematic literature reviews and primary observational studies

Supporting population sizing activities across research, business development, and long-range planning

Ability to thrive in a fast-paced matrixed environment and navigate multiple competing priorities

Exceptional written and oral communication skills with a keen ability to translate complex data into digestible information

Flexible, “outside the box” thinker who embodies a collaborative approach that embraces diverse perspectives

Culturally sensitive collaborator able to effectively lead cross-functional teams to drive alignment with business and stakeholder needs while managing timelines and budgets

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$204,200 - $306,200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Remote-Eligible

Flex Eligibility Status:

In this Remote-Eligible role, you can choose to be designated as:

1.    Remote: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select

2.    Hybrid: work remotely up to two days per week; or select

3.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Remote

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Director
Function
Biostatistics & Data Science
Therapeutic area
Not listed
Location
5000, United States
Employment type
Full time

How this role compares

Computed from every other active Biostatistics & Data Science role in our database, not just this employer's listings.

We currently track 83 comparable Director Biostatistics & Data Science roles across 32 biopharma companies.

83Comparable roles tracked
75Currently active
32Companies hiring similar roles
13Countries represented

Salary context

37 of 83 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $204,200/yr – $306,200/yr
Lowest disclosed · Principal Computational Statistician · Lilly $66,000/yr – $193,600/yr
Highest disclosed · Senior Director, Safety Data Sciences · AbbVie $206,500/yr – $393,000/yr
Peer group range $129,800 – $299,750 (median $215,000)

Where these roles are based

Top locations among the 83 comparable roles

United States56
India8
Canada4
United Kingdom4
China2
Germany2

+ 7 more countries

Seniority mix

83 of 83 peers have a known seniority level

Principal49
Director26
Senior Director8

Therapeutic area mix

10 of 83 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology5
Rare Disease4
Neuroscience1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Lilly Director
Same function Same seniority Same country

Open in 2 locations

Indianapolis, United StatesRemote, United States
60%similar
CSL Behring L.L.C. King of Prussia, United States Director
Same function Same seniority Same country
60%similar
Johnson & Johnson Titusville, United States Director
Same function Same seniority Same country
60%similar
Chiesi Farmaceutici Boston, United States Director
Same function Same seniority Same country
60%similar
Biogen Remote, United States Director
Same function Same seniority Same country
60%similar
Boehringer Ingelheim Ridgefield, Connecticut, United States Director
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new Biostatistics & Data Science job in the United States, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Director - Statistics
Lilly · Indianapolis, Indiana, United States of America · Director
Function Therapeutic area Seniority Country
60%
Director, Real World Evidence, Global Rare Diseases - HIDO (Boston, MA, US)
Chiesi Farmaceutici · Boston, United States · Director
Function Therapeutic area Seniority Country
60%
Sr Principal / Director TAM Statistician - Focus on Statistical Methodology and Simulation (Ridgefield, CT, United States, Connecticut)
Boehringer Ingelheim · Ridgefield, Connecticut, United States · Director
Function Therapeutic area Seniority Country
60%
Director, Statistical Programming
AstraZeneca · Waltham, Massachusetts, United States of America · Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.