Neurocrine Biosciences Inc. Posted October 2, 2026

Enterprise Architect Director

US CA San Diego, United States Full time
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Neurocrine Biosciences Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit  neurocrine.com , and follow the company on  LinkedIn ,  X , Facebook and YouTube . ( *in collaboration with AbbVie )

About the Role:

The Director, IT – Enterprise Architect serves as the enterprise architecture thought leader and provides strategic leadership for the enterprise architecture practice, defining the target-state architecture, standards, and multi-year technology roadmap that align IT investment with enterprise strategy. This role partners with business and IT leaders across research, drug development, manufacturing, quality, commercial, and G&A to translate business capability needs into scalable, compliant, and cost-effective solution architectures. The Director establishes the architecture governance model that guides enterprise technology and architecture decisions in validated and non-validated environments. _

Your Contributions (include, but are not limited to):

Define and drive the enterprise architecture vision, current and target-state architecture, and multi-year technology roadmap aligned to enterprise business strategy, Translating strategic business priorities into actionable technology direction and investment priorities

Establish, evolve and drive adoption of enterprise architecture frameworks, reference architectures, design principles, and architecture standards that enable consistent enterprise technology decisions

Lead the architecture governance process, including design authority forums, architecture review boards, and exception management

Conduct business capability assessments and capability-to-application mapping to identify gaps, redundancies, and investment priorities

Provide strategic architecture direction and expert guidance for end-to-end solutions across core enterprise platforms, including ERP, CRM, PLM, SCM, quality, laboratory, and financial systems

Define and influence enterprise-wide integration and API strategy, including middleware standards and B2B integration approaches

Define the enterprise data and analytics architecture direction and standards, covering data platforms, data domains, governance, and consumption patterns, in partnership with relevant functional experts

Establish and influence enterprise cloud, security, and AI architecture patterns in partnership with Infrastructure, Information Security, and Data Engineering functions

Ensure architecture designs satisfy GxP, data integrity, privacy, and computer system validation requirements, including 21 CFR Part 11 and GAMP 5 expectations, on a case-by-case basis

Provide strategic architecture leadership on M&A, divestiture, and in-licensing activity, including system integration, separation, and transition planning

Partner with sourcing and vendor management on technology selection, vendor evaluation, and build-versus-buy recommendations

Manage the architecture practice roadmap, budget, and external partner resources to deliver committed outcomes on time and within approved budget

Communicating and influencing alignment on architecture direction to executive stakeholders, translating complex technical concepts into business impact, enterprise risk and investment rationale

Anticipate and evaluate emerging technologies and industry trends and recommend and influence adoption of technologies and patterns that advance enterprise capability and efficiency

Requirements:

Bachelor's degree in computer science, Information Technology, Engineering, or related field AND

12+ years of progressive IT experience, including 8+ years in enterprise or solution architecture and 5+ years providing technical leadership for enterprise architecture initiatives, cross-functional teams, or complex technology programs

Master's degree in computer science, Information Technology, Engineering, or a related field (MBA preferred) and 10+ years as noted above

Strong command of integration architecture, including API management, event-driven patterns, and enterprise middleware

Working knowledge of modern data architecture, including cloud data platforms (Databricks, Snowflake, Redshift), lakehouse patterns, and data governance models

Experience architecting on public cloud (AWS or/and Azure), including landing zones, cost optimization, and cloud security patterns

Demonstrated knowledge and experience evaluating and architecting AI, generative AI, automation, and low-code solutions, including use case qualification and platform selection

Proven experience leading architecture for enterprise-scale portfolio rationalization and modernization programs, including architecture workstreams for mergers, acquisitions, divestitures, and system separations

Familiarity with software development practices, including agile/lean delivery, version control, code review, and CI/CD

Recognized internally as a thought leader and expert in expertise architecture, with broad expertise across related technology disciplines

Influences and negotiates with senior and executive leadership to secure alignment on technology direction and investment

Excellent communication, problem-solving, and analytical thinking skills

Sees the broader picture and anticipates upstream and downstream impacts across multiple functions, departments, and external partners

Demonstrated ability to lead complex, cross-functional programs and initiatives involving significant scope, interdependencies, risk, and organizational impact

Sets direction in ambiguous and complex situations, exercising advanced judgement, and making well-informed decisions with incomplete information

#LI-CL1

Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment , and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

_

The annual base salary we reasonably expect to pay is $195,700.00-$267,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

Job details

Seniority
Director
Function
Information Technology
Therapeutic area
Not listed
Location
US CA San Diego, United States
Employment type
Full time

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 120 comparable Director Information Technology roles across 35 biopharma companies.

120Comparable roles tracked
110Currently active
35Companies hiring similar roles
14Countries represented

Salary context

43 of 120 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $195,700/yr – $267,000/yr
Lowest disclosed · Principal SRE Engineer · Lilly $66,000/yr – $158,400/yr
Peer group range $112,200 – $288,150 (median $220,500)

Where these roles are based

Top locations among the 120 comparable roles

United States68
India33
Spain3
United Kingdom2
Greece2
Japan2

+ 8 more countries

Seniority mix

120 of 120 peers have a known seniority level

Principal67
Director40
Senior Director13

Therapeutic area mix

1 of 120 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
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60%similar
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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Function Therapeutic area Seniority Country
60%
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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.