Vertex Pharmaceuticals Inc (US) Posted October 14, 2026

Director, Project Management & Strategic Operations (Disease Strategy Team)

Boston, United States Full time
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Vertex Pharmaceuticals Inc (US) is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

General Summary: Vertex is seeking a talented strategic colleague to serve in a critical role supporting the Disease Strategy Team Program Office in the Office of the CEO. The Strategy & Operations Director will partner closely with a Disease Area Executive (DAE) to drive special initiatives to support a particular DST. We are seeking a candidate that has a strong track record in strategic roles, along with cross functional collaboration and effective communication skills to apply for this opportunity.

Key Duties and Responsibilities:

• Partners with DAE to lead strategic projects and high-profile initiatives

• Act as a liaison between cross functional colleagues to ensure alignment and coordination on a wide variety of cross-functional initiatives; Attends selected meetings on behalf of DAE

• Develops dashboards or other tools for reporting of KPIs, monitors ROI of key initiatives and identifies focus areas to drive action that accelerates our plan

• Drives the development of high-impact executive presentations

• Leads after action reviews of critical projects; provide recommendations for improvement of processes and systems Knowledge and Skills:

• Outstanding communication of information and ideas (written, PowerPoint, verbal), to varied audiences including senior and executive leadership

• Analytical, able to glean insights from data using excel and other tools, and communicate in a compelling, visual way

• Strong collaboration skills, with an ability to influence multiple stakeholders; builds mutual trust, respect and cooperation among team members

• Proven project management skills, including scenario analysis, business acumen and the ability to manage multiple tasks and priorities; adapt to new projects rapidly and effectively

• Strategic thinker with a track record of driving results

• Self-motivated; acts independently and prioritizes appropriately; embraces unexpected changes or challenges and drives to improved solutions in a fast-paced environment

• Proven ability to work in and influence a cross-functional team promoting collaboration and high performing team behaviors with an unwavering focus on what is best for the patients we serve

• Consistently displays sound ethics, good judgment and demonstrates Vertex’s core values

• Strong biopharmaceutical drug discovery and development acumen across multiple disciplines

Education and Experience:

• Bachelor's degree

• Advanced degree (MBA, PhD, or MD) or comparable experience preferred

• Typically 10+ years of progressive, relevant experience with demonstrated experience in strategy, project management, and organizing and directing multiple teams and departments in healthcare/biopharmaceuticals

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$185,400 - $278,200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1.    Hybrid: work remotely up to two days per week; or select

2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Director
Function
BD&L & Strategic Planning
Therapeutic area
Not listed
Location
Boston, United States
Employment type
Full time

How this role compares

Computed from every other active BD&L & Strategic Planning role in our database, not just this employer's listings.

We currently track 131 comparable Director BD&L & Strategic Planning roles across 46 biopharma companies.

131Comparable roles tracked
124Currently active
46Companies hiring similar roles
16Countries represented

Salary context

50 of 131 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $185,400/yr – $278,200/yr
Lowest disclosed · Principal Scientist II, Translational Biomarker Strategy Lead · Novartis $114,100/yr – $211,900/yr
Highest disclosed · Sr. Director, US Policy Strategy · CSL Behring L.L.C. $297,000/yr – $364,000/yr
Peer group range $163,000 – $330,500 (median $235,450)

Where these roles are based

Top locations among the 131 comparable roles

United States84
China19
United Kingdom5
Japan5
Switzerland4
France2

+ 10 more countries

Seniority mix

131 of 131 peers have a known seniority level

Director93
Senior Director30
Principal8

Therapeutic area mix

34 of 131 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology11
Neuroscience11
Immunology8
Respiratory2
Dermatology & Aesthetics1
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Amgen Inc. Remote, United States Director
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Boehringer Ingelheim Fremont, California, United States Director
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60%similar
Boehringer Ingelheim Ridgefield, Connecticut, United States Director
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Merck Rahway, New Jersey, United States Director
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AbbVie North Chicago, IL Director
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60%similar
AbbVie North Chicago, IL Director
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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new BD&L & Strategic Planning job in the United States, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.