AstraZeneca Posted November 5, 2026

Director Medical Affairs, Neurology (12-month contract)

Mississauga, Ontario, Canada Full time
Medical Affairs Neuroscience Director
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AstraZeneca is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life changing medicines. In-person working gives us the platform to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

This is a 12-month contract

Role Purpose

Provide scientific and medical leadership for the Canadian Neurology portfolio and lead, coach and develop the Medical Affairs team. Translate the Global Medical Affairs Plan into locally relevant strategies that address patient needs, clinical practice, healthcare-system priorities and access. Working across functions, advance evidence-based care, support health-system transformation and improve patient outcomes throughout the product lifecycle, from development and launch to indication expansion, post-launch optimisation and loss-of-exclusivity planning.

Key Responsibilities

Medical strategy: Develop and implement the annual Canadian medical plan, defining priorities, activities, timelines, resources and measures of impact. Incorporate unmet needs, treatment pathways, access considerations and collaborator insights; monitor results to improve planning and delivery.

Scientific leadership: Maintain current expertise in Neurology epidemiology, standards of care, guidelines, emerging science and evidence gaps. Apply this knowledge to medical priorities and cross-functional decisions. Communicate complex information accurately and objectively to and at the appropriate level for a variety of audiences.

Evidence generation: Identify Canadian evidence gaps and shape integrated research plans. Support or lead investigator-sponsored, real-world evidence, observational, health outcomes, post-authorisation and other interventional or non-interventional studies, ensuring scientific rigour, research ethics and compliance.

Scientific engagement and education: Build credible relationships with healthcare professionals, researchers, scientific experts,  and physician organisations, and other collaborators. Oversee balanced, non-promotional education, scientific exchange and timely responses to unsolicited enquiries. Gather, document, analyse and share unsolicited insights.Use emerging trends to inform strategy, education and risk management.

Cross-functional and global partnership: Provide objective medical leadership with Clinical Development, Regulatory Affairs, Market Access, Health Economics and Outcomes Research, Commercial, Patient Advocacy, Pharmacovigilance, Quality and Compliance. Maintain medical independence and clear separation of medical and promotional activities. Represent Canada in global and regional forums, sharing local insights and standard methodologies.

Governance: Ensure activities, materials and research meet Canadian legislation, regulatory expectations, industry codes and company procedures, including privacy, transparency, research ethics, healthcare-professional interactions and documentation. Review or approve content within the governance framework for accuracy and fair balance.

Patient safety: Recognise, manage and advance safety, quality, compliance and benefit–risk concerns, supporting adverse-event reporting, product-quality complaints and safety-signal identification.

Team leadership: Coach and develop the team, fostering scientific integrity, inclusion, innovation, collaboration, accountability and continuous learning. Lead through influence in a matrix organisation.

Operational leadership: Manage budgets and resources, track and document delivery against local and regional objectives, and improve effectiveness through appropriate technology, including artificial intelligence.

Qualifications and Experience

An advanced degree in medicine, pharmacy, life sciences or a related discipline, MD, PharmD, PhD or equivalent, is strongly preferred; relevant postgraduate clinical or scientific training is desirable.

7 years of experience in the pharmaceutical, biotechnology, healthcare or related industry, with a strong track record in Medical Affairs, medical communications or a comparable scientific function; at least 3 years coaching, mentoring or developing teams.

Experience developing and implementing medical strategies, annual plans and evidence-generation priorities across the product lifecycle, and contributing to or leading medical research. Sound understanding of research ethics, scientific governance and data interpretation.

Strong knowledge of Canadian healthcare, including federal and provincial collaborators, regional clinical practice, reimbursement and access, and the needs of rare disease patients, caregivers and healthcare professionals.

Working knowledge of Health Canada expectations, the Innovative Medicines Canada Code of Ethical Practices, the PAAB Code of Advertising Acceptance, privacy and research-ethics requirements, and company policies. Understanding of pharmacovigilance, risk management and appropriate critical issue.

Ability to build credible collaborator relationships, lead through influence and collaborate in a matrix environment.

Excellent written, verbal and presentation skills, with sound judgement in prioritising demands, managing resources and translating scientific insights into practical priorities while maintaining medical independence.

Demonstrated experience using artificial intelligence to improve efficiency, innovation and functional effectiveness.

Willingness to travel within Canada and internationally for scientific exchange, internal meetings, congresses and collaborator engagements, as required.

Desirable Additional Experience

Neurology expertise, particularly in generalized myasthenia gravis (gMG) and neuromyelitis optica spectrum disorder (NMOSD).

Experience in a Canadian affiliate or another regulated healthcare environment, including work with Canadian collaborators across regional differences in clinical practice, reimbursement and access.

Experience supporting launches, indication expansions, post-launch optimisation and loss-of-exclusivity planning.

Leadership of integrated evidence-generation plans; experience with investigator-sponsored research, publication planning, medical communications or medical review and cross-functional governance forums.

French-language capability where needed for Canadian collaborator engagement.

Working at Alexion

Join a collaborative, diverse culture that values innovation and offers the opportunity to make a meaningful difference in rare disease patients’ lives. Our hybrid approach supports in-person collaboration, with an expectation of working from the office, on average, a minimum of three days per week, balanced with individual flexibility.

Ready to lead and inspire? Apply now to join Alexion, AstraZeneca Rare Disease.

#LI-Hybrid

We are using AI as part of the recruitment process.

This advertisement relates to a current vacancy.

Job details

Seniority
Director
Function
Medical Affairs
Therapeutic area
Neuroscience
Location
Mississauga, Ontario, Canada
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 301 comparable Director Medical Affairs roles across 55 biopharma companies.

301Comparable roles tracked
284Currently active
55Companies hiring similar roles
32Countries represented

Salary context

120 of 301 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Principal Strategic Medical Writer · AbbVie $109,500/yr – $208,500/yr
Peer group range $159,000 – $392,100 (median $263,250)

Where these roles are based

Top locations among the 301 comparable roles

United States208
United Kingdom24
Canada8
China7
France6
Germany5

+ 26 more countries

Seniority mix

301 of 301 peers have a known seniority level

Director249
Senior Director37
Principal15

Therapeutic area mix

130 of 301 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology63
Neuroscience17
Immunology14
Cardiovascular / CVRM8
Rare Disease7
Respiratory6
Dermatology & Aesthetics6
Gastroenterology6
Ophthalmology2
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

85%similar
Ipsen Biopharm Ltd London (UK), United Kingdom Director
Same function Same therapeutic area Same seniority
85%similar
Regeneron Pharmaceuticals, Inc (USA) Sleepy Hollow, United States Director
Same function Same therapeutic area Same seniority
85%similar
E.R. Squibb & Sons,L.L.C. Princeton Pike, United States Director
Same function Same therapeutic area Same seniority
85%similar
E.R. Squibb & Sons,L.L.C. Princeton, United States Director
Same function Same therapeutic area Same seniority

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new Medical Affairs job in Canada, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

85%
Global Medical Affairs Director Neurosciences
Ipsen Biopharm Ltd · London (UK), United Kingdom · Director
Function Therapeutic area Seniority Country
85%
Senior Medical Director, Medical Affairs, Neurology
Regeneron Pharmaceuticals, Inc (USA) · Sleepy Hollow, United States · Director
Function Therapeutic area Seniority Country
85%
Director, WW Medical Neuroscience, Medical Communications
E.R. Squibb & Sons,L.L.C. · Princeton Pike, United States · Director
Function Therapeutic area Seniority Country
85%
Director, Global Medical Neuroscience, Psychiatry, Mood Disorders
E.R. Squibb & Sons,L.L.C. · Princeton, United States · Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.