AbbVie Posted September 25, 2026

Director, Head of Molecular Discovery Technologies

North Chicago, IL Full-time
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AbbVie is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  www.abbvie.com . Follow @abbvie on  LinkedIn,   Facebook ,  Instagram ,  X  and  YouTube.

Job Description

Summary

We are seeking an accomplished scientific and organizational leader to serve as Head of Molecular Discovery Technologies (MDT) team. This leader will define the strategic direction of a multidisciplinary organization spanning DNA-Encoded Libraries (DEL), protein NMR, mass spectrometry-based affinity screening platform development, mass spectrometry-based structural characterization, and emerging molecular discovery technologies. Together, these capabilities accelerate hit discovery, improve hit quality, and enable small-molecule and peptide discovery programs across therapeutic areas.

The leader will report to the Head of Target Enabling Technologies organization and serve on the extended leadership team of Small Molecule Therapeutics and Platform Technologies. Partnering across functions, the leader will help shape portfolio-level lead discovery strategies and drive the evolution of lead discovery through platform innovation, integrated data strategies, and AI/ML-enabled approaches.

The role requires a strategic and collaborative scientific leader who can translate emerging technologies and data insights into scalable discovery capabilities, stronger portfolio decisions, and measurable pipeline impact, while developing talent and maintaining external scientific visibility.

Responsibilities

Strategic Leadership

Define and execute the Molecular Discovery Technologies strategy to maximize portfolio impact through accelerated hit discovery and improved hit quality.

Lead MDT portfolio prioritization and resource allocation, aligning platform deployment and investments with the highest-value discovery opportunities.

Drive integrated data strategies that connect experimental, screening, and computational insights, leveraging AI/ML-enabled approaches to improve decision quality and discovery effectiveness

Partner with Molecular Screening and Characterization, Computational Drug Discovery, Medicinal Chemistry, Peptide Therapeutics, and other leaders to shape future lead-discovery approaches and cross-functional technology investments.

Develop long-range MDT technology, talent, and infrastructure plans aligned with future portfolio needs.

Establish metrics for platform performance, portfolio contribution, and organizational effectiveness.

Scientific Leadership

Provide scientific and strategic oversight to ensure platform-generated insights inform hit identification, prioritization, and progression decisions.

Lead teams in solving complex scientific problems and developing fit-for-purpose solutions.

Drive scientific rigor and decision quality while ensuring technologies translate into actionable portfolio outcomes.

Guide the evaluation, development, and adoption of emerging molecular discovery technologies based on scientific need and potential portfolio impact.

Represent Molecular Discovery Technologies as a key scientific partner on cross-functional teams.

Establish and maintain external scientific relationships and drive adoption of innovative technologies and best practices that enhance discovery effectiveness and portfolio impact.

Talent and Organizational Leadership

Build and lead a high-performing multidisciplinary organization capable of delivering sustained impact across the portfolio.

Develop scientific and people leaders through coaching, mentoring, and succession planning.

Create clear goals, performance expectations, and accountability frameworks aligned with portfolio priorities.

Drive operational excellence, resource stewardship, and continuous improvement across all platforms.

Foster a culture of scientific excellence, inclusion, constructive challenge, agility, cross-functional collaboration, and innovation with purpose.

Qualifications

Ph.D. in chemistry, medicinal chemistry, biochemistry, biophysics, or a related discipline.

10+ years of industry experience in lead discovery and/or molecular discovery technologies.

Strong background in medicinal chemistry and lead discovery strategy.

Demonstrated success leading scientific functions or platform teams in a matrixed research environment.

Recognized scientific leader with a strong external reputation demonstrated through publications, invited presentations, patents, scientific leadership, or other evidence of sustained impact in the field.

Experience applying AI/ML or advanced analytics to discovery data is preferred.

Excellent leadership, communication, influencing, and collaboration skills.

Preferred Qualifications

Experience guiding platform development in DEL, NMR, mass spectrometry, or related discovery technologies.

Demonstrated success translating new technologies into scalable discovery capabilities and portfolio outcomes.

Experience developing scientific talent and building succession depth.

Broad awareness of emerging molecular discovery methods and industry trends.

Leadership Competencies

Strategic thinking and functional leadership

Scientific rigor and sound judgment

Cross-functional influence

Talent development and coaching

Collaboration and relationship building

Accountability for results

Innovation and problem-solving

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

This job is eligible to participate in our long-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit  https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Job details

Seniority
Director
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
North Chicago, IL
Employment type
Full-time

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 133 comparable Director Drug Discovery & Preclinical Research roles across 35 biopharma companies.

133Comparable roles tracked
126Currently active
35Companies hiring similar roles
11Countries represented

Salary context

68 of 133 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $160,500/yr – $305,000/yr
Lowest disclosed · Principal Scientist--Pharmacokinetics, Dynamics and Metabolism · Pfizer $106,000/yr – $176,600/yr
Peer group range $141,300 – $322,000 (median $213,875)

Where these roles are based

Top locations among the 133 comparable roles

United States112
China5
United Kingdom3
India3
China's Mainland2
Switzerland2

+ 5 more countries

Seniority mix

133 of 133 peers have a known seniority level

Principal80
Director38
Senior Director15

Therapeutic area mix

24 of 133 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology9
Immunology5
Neuroscience3
Cardiovascular / CVRM3
Respiratory2
Vaccines & Infectious Disease1
Gastroenterology1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
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60%similar
Gilead Sciences, Inc. Foster City, United States Director
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60%similar
Amgen Inc. Cambridge, United States Director
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60%similar
Amgen Inc. Thousand Oaks, United States Director
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60%similar
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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.