Business Performance Manager Supply Chain AXP
About this opportunity
Career Category
Supply Chain
Job Description
Manager, Business Performance - Amgen External Planning
Role Summary
The Manager, Business Performance drives strategic improvements to AXP processes and ways of working, while delivering data-driven insights across the organization. The role helps shape AXP's digital strategy and enables smarter planning and supply chains across internal and external manufacturing through analytics, AI, and technology.
The Manager owns improvements to the AXP Process Framework across Plan, Source, Make, Deliver, and Enable. In partnership with the Business Delivery Office (BDO) and Amgen Digital and Technology teams, the role standardizes workflows, identifies process gaps, and advances digital transformation.
The role works with Global, Regional, and Site Supply Chain teams, Global Distribution, Contract Quality Management, Operations Finance, Global Planning, and AXP Regional Hubs. It supports performance visibility across commercial and pre-commercial supply, integrated business planning, operational excellence, digital adoption, and compliance.
Roles and Responsibilities
Improve and Govern AXP Processes
· Own and improve the AXP Process Framework across Plan, Source, Make, Deliver, and Enable.
· Standardize end-to-end workflows, roles, and handoffs across functions, regions, and sites.
· Identify process gaps, risks, duplication, and unclear handoffs; maintain process maps, RACI matrices, work instructions, job aids, and guidance documents.
· Work with AXP Compliance and the BDO to manage changes to SOPs and approved documents.
· Apply Lean Business Systems and Operational Excellence methods to improve processes and ways of working.
Lead Continuous Improvement and Automation
· Use process analysis and value stream mapping to identify and prioritize continuous improvement, automation, and quick-win projects.
· Develop business justifications that define expected benefits, ROI, cost avoidance, and cost savings.
· Track project outcomes and confirm whether expected benefits are achieved.
Advance Digital Transformation and Smart Supply Chains
· Help shape and deliver AXP's digital strategy and transformation initiatives.
· Identify practical uses of data, analytics, AI, and automation to improve internal and external manufacturing, planning, and supply chain processes.
· Partner with Amgen Digital and Technology teams to define business needs and develop scalable solutions.
· Translate business needs into system and reporting requirements; support implementation, adoption, and ongoing monitoring of solutions.
Monitor Business and Financial Performance
· Track AXP Supply Chain and Finance metrics with Operations Finance and Global Planning.
· Maintain and improve KPI dashboards, reporting tools, and metric definitions; analyze performance across commercial and pre-commercial supply.
· Identify important trends, variances, risks, and KPIs requiring immediate attention; share insights and coordinate follow-up actions with the appropriate owners.
· Support visibility of agreed measures, including cost to serve, productivity, capacity, inventory, logistics, and financial plan or forecast variances.
· Support Quarterly Business Reviews (QBRs), Integrated Business Planning (IBP), and forward 12-quarter strategy discussions.
· Present data and analysis clearly to support business decisions.
Partner Across AXP and Global Functions
· Align priorities with the AXP Supply Execution Manager and BDO Manager.
· Partner with Global, Regional, and Site Supply Chain teams, Global Distribution, Contract Quality Management, Operations Finance, Global Planning, and AXP Regional Hubs.
· Support integrated processes and systems across regions and functions, working effectively across the US, Europe, and JAPAC time zones.
Lead Projects and Develop Team Capability
· Lead cross-functional projects and manage multiple priorities with minimal direction.
· Advise leaders on options, risks, and solutions for complex issues.
· Coach and develop team members; support capability building, succession planning, and engagement.
· Promote accountability, collaboration, and continuous improvement.
Tools and Systems
Familiarity with modern supply chain and business performance tools is preferred:
· Supply chain and enterprise planning: SAP S/4HANA, Kinaxis RapidResponse, or other enterprise planning systems.
· Process mapping: iGrafx, Microsoft Visio, or Lucidchart.
· Analytics and reporting: Tableau or similar business intelligence tools.
· Process management: process monitoring, process governance, and controlled documentation.
Basic Qualifications
Candidates must meet one of the following education and experience requirements:
· Doctorate degree and at least 3 years of Supply Chain, Business Analytics, or Operations experience; or
· Master's degree and at least 8 years of relevant experience; or
· Bachelor's degree and at least 10 years of relevant experience.
In addition, candidates must have at least 2 years of experience directly managing or leading projects or programs.
Preferred Qualifications
· Experience leading cross-functional process standardization or improvement initiatives.
· Lean Six Sigma experience; Green Belt certification preferred.
· Strong analytical mindset and experience using data to identify business opportunities.
· Experience applying analytics, AI, or automation to supply chain processes.
· Ability to identify quick wins and develop business justifications, including ROI, cost avoidance, and cost savings.
· Experience in pharmaceutical or biotech supply chains and GMP-regulated environments.
· Understanding of internal and external manufacturing, including CMO/CDMO operations.
· Experience with KPI dashboards, performance reporting, or KPI governance.
· Experience supporting QBRs, IBP, or Long-Range Strategy cycles.
· Strong project management, communication, presentation, and financial skills, including cost to serve, productivity, and capacity.
Soft Skills
· Growth mindset and willingness to learn, adapt, and improve.
· Uses sound judgment and is willing to take calculated risks to move work forward.
· Flexible and effective when collaborating across global time zones.
· Seeks feedback, reflects on it, and applies it to improve performance.
· Strong stakeholder management and relationship-building skills.
· Constructive, accountable, and patient-focused attitude.
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Job details
How this role compares
Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.
We currently track 661 comparable Manager Manufacturing & CMC roles across 88 biopharma companies.
Salary context
205 of 661 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 661 comparable roles
+ 35 more countries
Seniority mix
661 of 661 peers have a known seniority level
Therapeutic area mix
9 of 661 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
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How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.