Associate Scientist, In Vitro Pharmacology

Use Your Power for Purpose

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. In this role, you will contribute to the discovery and advancement of innovative medicines for patients worldwide by applying rigorous science, modern pharmacology, and cutting-edge technologies. Your work will help transform promising therapeutic ideas into high-quality experimental data that enable confident decisions across the drug discovery process.

What You Will Achieve

A key strategic focus within the Internal Medicine Research Unit (IMRU) is the discovery of novel therapies for obesity, cardiovascular disease, and related cardiometabolic conditions. As an Associate Scientist in the In Vitro Pharmacology group, you will contribute to early drug discovery programs by generating rigorous, reproducible pharmacology data that support target validation, assay development, compound profiling, and mechanism-of-action studies. This role is well suited for a collaborative, hands-on scientist with experience in cell-based assay execution, mammalian cell culture, quantitative data analysis, and an interest in receptor pharmacology within cardiometabolic drug discovery.

How You Will Achieve It

Develop, optimize, and execute cell-based signaling, ligand-binding, and other in vitro pharmacology assays to generate high-quality data that support project decisions.

Support compound profiling and mechanism-of-action studies through careful experimental design, troubleshooting, and quantitative data analysis.

Maintain mammalian cell cultures and prepare fit-for-purpose cellular or membrane-based assay reagents to support screening, binding, and functional assay workflows.

Apply core pharmacology concepts, including ligand potency, efficacy and affinity to interpret experimental results.

Work collaboratively with pharmacology colleagues and cross-functional project teams to support experimental priorities, data interpretation, and program objectives.

Summarize and communicate experimental findings clearly in team meetings, project discussions, and written updates.

Maintain accurate, timely, and compliant experimental records in an electronic laboratory notebook.

 

Qualifications

Must-Have

Bachelor’s degree with any years of laboratory experience.

 

Nice- to-Have

Hands-on experience with mammalian cell culture and cell-based assay execution.

Familiarity with core pharmacology concepts, concentration-response analysis, and principles of robust assay execution.

Experience analyzing and visualizing pharmacology data using Microsoft Excel, GraphPad Prism, or similar tools.

Interest in receptor pharmacology, GPCR signaling, obesity or cardiometabolic drug discovery.

Exposure to compound profiling, screening workflows, assay miniaturization, membrane-based assays, second messenger signaling assays, or emerging technologies to interrogate receptor function is preferred but not required.

Ability to organize, execute, and troubleshoot experiments with attention to detail, scientific rigor, and data quality.

Strong verbal and written communication skills, including the ability to present experimental results in individual and group settings.

Ability to manage multiple priorities and contribute effectively to a collaborative, cross-functional research environment.

Scientific curiosity, enthusiasm for learning, and motivation to contribute to the discovery of new medicines for patients.

Work Location Assignment: On Premise

The annual base salary for this position ranges from $60,200.00 to $100,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

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To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on  Pfizer Careers .

Research and Development