Novartis Posted November 10, 2026

Associate Director, AI Security Architecture

Prague, Czech Republic FULL_TIME
Information Technology Associate Director
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About this opportunity

Internal Job Title: Assoc. Dir. DDIT ISC Security Architecture AI#LI-HybridLocation: PragueRelocation Support: This role is based in Prague. Novartis is unable to offer relocation support: please only apply if accessible.Help shape how AI can be built, deployed, and scaled securely. In this role, you’ll influence the security architecture behind next-Generation AI solutions, defining standards and patterns that protect AI models, data, pipelines, and agentic systems throughout their lifecycle. You’ll work at the intersection of AI, cybersecurity, cloud engineering, and architecture, partnering with technical teams to address emerging threats, strengthen secure AI development, and turn evolving security challenges into practical, scalable solutions.

Key ResponsibilitiesLead AI architectural activities and develop secure solution architectures across business and technology domains.Define AI security standards and best practices for protecting AI pipelines, datasets, models, and infrastructure.Develop logical architecture designs and strategies to secure the organization’s AI domain and infrastructure.Establish and evolve AI architecture governance frameworks, including methods, practices, standards, and reusable architecture patterns.Assess the AI landscape, identifying and mitigating security risks across model training, deployment, and operations.Evaluate AI security technologies and integrate appropriate security controls across AI platforms and Large Language Models.Secure AI and agentic systems against model poisoning, adversarial inputs, prompt injection, jailbreaking, and emerging threats.Design Model Context Protocol servers, AI agent workflows, secure deployment architectures, and AI gateway integrations.Build Python services, developer tools, integrations, and AI security harnesses supporting secure software development.Collaborate with data scientists, engineers, and DevOps teams to embed security throughout the AI development lifecycle.Essential Requirements12+ years of overall professional experience, including substantial experience across security, architecture, software development, and AI security engineering.At least 5 years of security experience, 5 years in architecture, 5 years in development, and 2+ years in AI security and engineering.Proven AI security architecture expertise covering training data, models, pipelines, deployed AI solutions, security policies, standards, and architecture patterns.Strong knowledge of AI threats, risk identification, threat modeling, data privacy, and defenses against adversarial and AI-based attacks.Hands-on experience securing Artificial Intelligence and Machine Learning applications across cloud platforms, with strong Amazon Web Services engineering and architecture expertise.Production experience with AI coding agents, Model Context Protocol servers, agent workflows, Python development, automated testing, and AI gateway integrations.Desirable RequirementsSecurity engineering or application security background, with experience evaluating and working with specialized AI security technologies.Experience building developer-facing command-line tools and working effectively in multi-vendor, global technology environments.The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.You’ll receive (CZ only):Monthly pension contribution matching your individual contribution up to 3% of your gross monthly base salary; Risk Life Insurance (full cost covered by Novartis); 5-week holiday per year; (1 week above the Labour Law requirement) ; 4 paid sick days within one calendar year in case of absence due to sickness without a medical sickness report; Cafeteria employee benefit program – choice of benefits from Benefit Plus Cafeteria in the amount of 1,500 CZK per year; Meal vouchers in amount of 105 CZK for each working day (full tax covered by company); Car Allowance; MultiSport Card. Find out more about Novartis Business Services: https://www.novartis.cz/Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.Read our brochure to learn more about our global total rewards offering: https://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdfNote: Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable. A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the application process.Commitment to Diversity & Inclusion:Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all  individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an email to di.cz@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Job details

Seniority
Associate Director
Function
Information Technology
Therapeutic area
Not listed
Location
Prague, Czech Republic
Employment type
FULL_TIME

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 672 comparable Associate Director Information Technology roles across 68 biopharma companies.

672Comparable roles tracked
613Currently active
68Companies hiring similar roles
36Countries represented

Salary context

83 of 672 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Highest disclosed · Dir/Sr. Dir - Lab Automation Engineer, Discovery Oncology · Lilly $180,000/yr – $297,000/yr
Peer group range $98,050 – $238,500 (median $170,100)

Where these roles are based

Top locations among the 672 comparable roles

India257
United States215
Spain49
Poland29
United Kingdom17
Philippines11

+ 30 more countries

Seniority mix

672 of 672 peers have a known seniority level

Senior393
Manager190
Associate Director89

Therapeutic area mix

5 of 672 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology4
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Novartis Prague, Czech Republic Associate Director
Same function Same seniority Same country
60%similar
Novartis Prague, Czech Republic Associate Director
Same function Same seniority Same country
60%similar
Novartis Prague, Czech Republic Associate Director
Same function Same seniority Same country
50%similar
Sandoz Prague, Czech Republic Senior
Same function Adjacent seniority Same country
50%similar
Novartis Prague, Czech Republic Senior
Same function Adjacent seniority Same country
50%similar
Novartis Prague, Czech Republic Senior
Same function Adjacent seniority Same country

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Associate Director - AI Infrastructure Architect (AI Factory)
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Function Therapeutic area Seniority Country
50%
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Sandoz · Prague, Czech Republic · Senior
Function Therapeutic area Adjacent seniority Country
50%
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Novartis · Prague, Czech Republic · Senior
Function Therapeutic area Adjacent seniority Country
45%
Assoc Director, IT SAP MDM and Data Governance
Gilead Sciences, Inc. · Foster City, United States · Associate Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.