Associate Director, ADC (Suzhou, JS, CN, 215123)

苏州，中国   |   全职   |   Job ID: 11911

About the role:

As Associate Director, you will lead linker–payload chemistry and novel payload discovery for antibody–drug conjugates, helping advance differentiated therapeutic candidates. Your work supports BioNTech's mission to develop new treatment approaches for cancer.Based in Suzhou, you will build chemistry and bioconjugation capabilities and lead a specialist team. Working with colleagues across discovery, biology, drug metabolism, safety and process development, you will help guide programs from early research toward preclinical candidate selection.

Your contribution:

Set the chemistry strategy for antibody–drug conjugate programs, aligning linker–payload platforms and emerging mechanisms with target biology and portfolio needs

Design, synthesize and optimize linker–payload systems for potency, solubility, stability, controlled release and conjugation compatibility

Establish bioconjugation, purification and analytical workflows with clear quality criteria for conjugates

Evaluate new payload classes and mechanisms, and integrate chemistry, efficacy, drug metabolism and safety data to guide optimization and candidate selection

Build and lead a chemistry and conjugation team, while planning resources and developing team membersDirect external collaborations and support robust documentation, intellectual property generation, safe handling and technology transfer

A good match:

PhD in organic chemistry, medicinal chemistry, chemical biology, pharmaceutical sciences or a related fieldBiopharmaceutical industry experience in antibody–drug conjugate linker–payload chemistry, medicinal chemistry and bioconjugation, including hands-on and supervisory work

Track record designing and optimizing linker–payload systems and advancing antibody–drug conjugate programs; experience with novel payload classes is an advantage

Strong knowledge of synthetic and medicinal chemistry, linker design, payload derivatization, structure–activity relationships and conjugation-compatible molecular design

Proficiency in interpreting nuclear magnetic resonance, liquid chromatography–mass spectrometry, high-performance liquid chromatography and conjugate analytics

Fluent English, with the ability to write and present technical information, negotiate technical matters and collaborate across borders; team leadership experience is preferred

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我们诚挚期待您的加入。