Amgen Inc. Posted August 20, 2026

Sr Engineer Industrial Engineering

Holly Springs, United States Full time
Manufacturing & CMC Senior

Amgen Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Engineering

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

SR ENGINEER INDUSTRIAL ENGINEERING

What you will do

Let’s do this. Let’s change the world. In this vital role you will support Drug Substance Operations by driving manufacturing performance, capacity optimization, labor productivity, and operational excellence initiatives. You will apply Industrial Engineering principles, Lean methodologies, and advanced analytical tools to improve throughput, resource utilization, and operational effectiveness across manufacturing and support functions.

Conduct capacity assessments, equipment/labor modeling, staffing analyses, and operational readiness evaluations to support business objectives.

Develop and implement solutions that improve throughput, reduce work-in-process inventory, and enhance productivity.

Optimize equipment utilization, process area capacity, manufacturing performance, and facility space utilization.

Support strategic planning activities through quantitative analysis and scenario modeling.

Perform facility layout, workflow, and resource optimization analyses.

Support new product introductions and technology implementations by assessing impacts to capacity, staffing, and manufacturing systems.

Lead continuous improvement projects utilizing Lean, Six Sigma, and Operational Excellence methodologies.

Partner with Manufacturing, Engineering, Quality, Supply Chain, and Process Development organizations to identify and execute improvement opportunities.

Facilitate Kaizen events and support implementation of Visual Management, 5S, Standard Work, and Mistake Proofing practices.

Communicate recommendations, project updates, and performance metrics to functional leaders.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The high-performing professional we seek is an effective leader with strong cross-functional project management and communication skills with these qualifications.

Basic Qualifications:

High school diploma / GED and 10 years of Engineering and/or Manufacturing experience OR

Associate’s degree and 8 years of Engineering and/or Manufacturing experience OR

Bachelor’s degree and 4 years of Engineering and/or Manufacturing experience OR

Master’s degree and 2 years of Engineering and/or Manufacturing experience OR

Doctorate degree

Preferred Qualifications:

Degree in Industrial Engineering or related discipline.

Experience in pharmaceutical or biotechnology manufacturing operations.

Experience with capacity planning, labor models, and operational analysis.

Knowledge of Lean Manufacturing and Six Sigma methodologies.

Experience with data analytics, visualization, and statistical analysis tools.

Knowledge of AI and digital solutions to improve operational performance.

Experience with simulation and planning tools such as Virtecs, SAP, or similar platforms.

Strong analytical and problem-solving skills.

Strong facilitation and project management skills.

Self-directed and able to work independently with minimal supervision.

Effective influencing and persuasion skills across all organizational levels.

Strong verbal, written, and presentation skills.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

. Salary Range

115,494.60USD -156,257.40 USD

Job details

Seniority
Senior
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Holly Springs, United States
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 482 comparable Senior Manufacturing & CMC roles across 63 biopharma companies.

482Comparable roles tracked
446Currently active
63Companies hiring similar roles
26Countries represented

Salary context

221 of 482 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Senior Scientist II – CMC Developmental Sciences · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Peer group range $0 – $222,900 (median $150,600)

Where these roles are based

Top locations among the 482 comparable roles

United States335
India39
Ireland16
Netherlands11
Singapore9
United Kingdom9

+ 20 more countries

Seniority mix

482 of 482 peers have a known seniority level

Senior308
Principal98
Associate Director76

Therapeutic area mix

1 of 482 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Respiratory1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Lilly San Diego, California, United States of America Senior
Same function Same seniority Same country
60%similar
Seagen Inc Washington – Bothell, United States Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
AbbVie Worcester, MA Senior
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Sr. Scientist - Lab Automation Scientist
Lilly · San Diego, California, United States of America · Senior
Function Therapeutic area Seniority Country
60%
Senior Scientist II, Automation Engineering
AbbVie · North Chicago, IL · Senior
Function Therapeutic area Seniority Country
60%
Senior Scientist, siRNA Screening Automation and Molecular Analytics
AbbVie · Worcester, MA · Senior
Function Therapeutic area Seniority Country
60%
Sr Scientist I, Automation Development
AbbVie · North Chicago, IL · Senior
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.