AstraZeneca Posted July 16, 2026

【Alexion Japan】Head of Medical Affairs, Rare Bone & Endocrine Disorders, Rare Tumours

Minato-ku, Tokyo, Japan Full time
Medical Affairs Oncology

AstraZeneca is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

This is what you will do:

This position, Head of Medical Affairs Rare Bone & Endocrine Disorders, Rare Tumours will provide strategic leadership to Alexion’s assigned therapeutic area portfolio, including in-line and pipeline assets. Responsible for providing deep scientific and medical expertise and a strong understanding of disease biology, patient journey, and treatment landscape in the responsible therapeutic area. Responsible for the development and implementation of the strategic plans for multiple compounds and indications in a strongly matrixed environment with effective cross-functional collaboration.

This role will collaborate with Global, Regional and Japan Medical Affairs stakeholders to maximize patients’ outcomes by setting and continuously advancing the evidence-based medical standard of care.

Lead and develop Medical Leads, MSL leadership and broader matrix medical organization as applicable.

You will be responsible for:

Develop and implement local medical strategies and plans as well as the strategically aligned tactical plan (and oversee their execution) across assets, indications, lifecycle stages, and evidence-generation priorities within the responsible Rare Bone & Endocrine Disorders,Rare Tumours area. Will work cross-functionally as well as closely with the regions and countries to transform medical practice. Responsible for the following:

The Head of Medical Affairs Rare Bone & Endocrine Disorders, Rare Tumours ensures solid scientific medical planning and execution to positively impact outcomes for patients within the responsible disease area

Responsible for ensuring the quality of medical strategies in Japan in alignment with Alexion's corporate and brand strategies.

Accountable for day-to-day operations execution, ensuring the quality and strategic alignment of medical activities for building local evidence and trust with external experts, healthcare professionals, patient communities, and internal stakeholders.

Represent Japan Medical Affairs for the responsible therapeutic area at relevant Global and Japan Product Teams.

Leads the organization to ensure the effectiveness and efficiency of operations through continuous improvement approaches, formulating and developing strategic directions, business/resource planning, appropriate budget management, and leadership of medical organizations.

Ensures that the organization’s strategy is aligned with global and regional medical strategies and enterprise priorities for the relevant therapeutic area.

Responsible for related HR activities such as talent development, evaluation, and recruitment.

Partners cross-functionally with Commercial, Market Access, Clinical Development, Regulatory, Safety, and other relevant functions.

As a member of the Medical Affairs Leadership Team (MALT), this role contributes to the success of the entire medical department across all functions and roles, embedding Alexion’s corporate values, culture, and vision across the broader medical organization.

Ensure that the medical organization is a trusted cross-functional partner to Commercial and other relevant functions, through effective internal communication, participation in the JLC, cross-functional engagement, and execution of medical activities.

Escalate key issues and present recommendations/solutions to the Medical Leadership Team (MALT) and/or JLC as necessary.

You will need to have:

Must have MD, PhD, or PharmD level degree or equivalent

Must have experience in a Global or International Medical Affairs function (5+ years)

Excellent communication skills both written and verbal.

Experience and ability to work in a matrixed cross-functional environment, both internally and remotely

Excellent interpersonal skills with demonstrated ability to drive results as an effective team member and project leader.

Proven ability to manage budget and resources

Strong business acumen

Ability to build effective partnerships between HQ and affiliates

Flexibility and ability to adapt to changing conditions

Excellent problem solving, organizational, and negotiating skills

Must demonstrate energy and enthusiasm, bringing a positive approach to challenges, along with a strong sense of ethics and responsibility

Travel required up to 25%

Preferred qualifications include:

Scientific and technical acumen in the relevant therapeutic area

Understanding of evidence generation, health economics and outcomes research, and access/reimbursement environment

Understanding of global and local healthcare environments, stakeholder needs, and access considerations

Date Posted

16-7月-2026

Closing Date

14-7月-2027

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com . Alexion participates in E-Verify.

Job details

Seniority
Not listed
Function
Medical Affairs
Therapeutic area
Oncology
Location
Minato-ku, Tokyo, Japan
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 924 comparable Medical Affairs roles across 130 biopharma companies.

924Comparable roles tracked
800Currently active
130Companies hiring similar roles
58Countries represented

Salary context

175 of 924 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Lowest disclosed · Clinical Coordinator · Pfizer $79,400/yr – $132,400/yr
Peer group range $105,900 – $458,800 (median $232,750)

Where these roles are based

Top locations among the 924 comparable roles

United States379
China's Mainland69
Japan60
China57
India50
Germany40

+ 52 more countries

Seniority mix

502 of 924 peers have a known seniority level

Director148
Manager125
Senior97
Associate55
Associate Director39
Senior Director20
Executive/VP11
Principal5
Intern/Fellow/Postdoc2

Therapeutic area mix

325 of 924 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology113
Immunology52
Neuroscience35
Cardiovascular / CVRM34
Respiratory21
Vaccines & Infectious Disease21
Rare Disease21
Dermatology & Aesthetics20
Gastroenterology4
Ophthalmology4

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

80%similar
Amgen K.K. Tokyo, Japan
Same function Same therapeutic area Same country
80%similar
Gilead Sciences K.K. Tokyo, Japan Associate Director
Same function Same therapeutic area Same country
80%similar
Gilead Sciences K.K. Tokyo, Japan
Same function Same therapeutic area Same country
80%similar
Pfizer Japan Inc. Tokyo, Japan Associate
Same function Same therapeutic area Same country
80%similar
Pfizer Japan Inc. Tokyo, Japan Manager
Same function Same therapeutic area Same country
80%similar
AstraZeneca Minato-ku, Tokyo, Japan Associate
Same function Same therapeutic area Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

80%
Medical Science Liaison for lung cancer
Amgen K.K. · Tokyo, Japan · Seniority not listed
Function Therapeutic area Seniority Country
80%
[MA] Associate Mgr/Mgr, Lung Cancer, ONC, MAS
Pfizer Japan Inc. · Tokyo, Japan · Associate
Function Therapeutic area Seniority Country
65%
Early Development Lead Medical Director, Non-oncology
Roche · Shanghai, Shanghai, China's Mainland · Director
Function Therapeutic area Seniority Country
65%
Scientific Director / Senior Medical Director, Multiple Myeloma (International Medical Affairs)
AbbVie · Mettawa, IL · Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.