Senior Director, Patient Safety Compliance Excellence
About this opportunity
The Senior Director, Pharmacovigilance Compliance is a critical leadership role within Patient Safety, responsible for the global governance and continuous improvement of compliance controls across the AstraZeneca pharmacovigilance landscape. The role drives both strategic and operational compliance by implementing robust predictive and detective controls, fostering an enterprise-wide safety and compliance culture and shaping policy. Key elements include championing the use of analytics, innovating compliance frameworks, developing compliance policies and standards, and partnering with QPPV to ensure optimal compliance and readiness globally through prediction and early detection.
Typical Accountabilities
Accountable for the global pharmacovigilance compliance model, encompassing preventive, detective, and corrective controls.
Leads innovation in predictive compliance using advanced analytics and digital platforms to proactively identify and manage risks.
Develops and maintains detective monitoring frameworks, including dashboards, that cover quality issues, audit findings, and root cause analysis information.
Promotes and supports the development of global PV policies/procedures ensuring international alignment and regulatory compliance.
Drives timely and sustainable preventive and corrective actions, embedding improvements into compliance frameworks and governance.
Maintains compliance governance models and ensures effective engagement in governance meetings, such as PV council.
Sponsors safety and compliance culture across Patient Safety; supports training, communication, and best/global standard practice dissemination.
Partners closely with Inspection Excellence to ensure integrated compliance and inspection readiness approaches.
Represents Patient Safety externally with regulators and in professional forums; ensures continual advocacy and knowledge leadership.
Develops and mentors a high-performing, globally distributed team, championing talent and professional development.
Provides comprehensive compliance reporting and strategic recommendations to QPPV/senior leadership.
Minimum Requirements:
University degree (or equivalent) in a scientific/healthcare discipline
Extensive experience in pharmacovigilance, regulatory compliance, patient safety
Demonstrated global QA and compliance leadership
Thorough knowledge of directive, preventive, detective, and corrective controls
Proven digital compliance/predictive analytics track record
Cross-functional global experience (matrix working)
Strong US/global compliance environment experience
Excellence in communication, advocacy, and talent development
Desirable Skills:
PhD or equivalent in scientific discipline
Experience with digital transformation, Lean/process improvement
Financial awareness/oversight
Familiarity with new/emerging regulatory requirements
Experience with external engagement (industry, regulators)
Date Posted
24-Jul-2026
Closing Date
30-Aug-2026
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Job details
How this role compares
Computed from every other active Pharmacovigilance role in our database, not just this employer's listings.
We currently track 16 comparable Senior Director Pharmacovigilance roles across 9 biopharma companies.
Salary context
3 of 16 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 16 comparable roles
Seniority mix
16 of 16 peers have a known seniority level
Therapeutic area mix
7 of 16 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.