Director, Principal Patient Safety Scientist Oncology
About this opportunity
Location: Barcelona, Spain (on-site) 3 days working from the office and 2 days working from home.
Do you have expertise in, and passion for Pharmacovigilance? Would you like to apply your expertise to lead on complex PV projects in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.
We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. The pioneers, we make bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what’s next.
What you'll do
The Director, Principal Patient Safety Scientist within Oncology Patient Safety is the highest level individual contributor scientist in our team structure before a team member elects to stay in technical project facing tract or moving into leadership tract leading and managing individuals within our organization. We are looking for someone who can demonstrate leadership within our environment and lead on complex PV projects through safety science expertise . You will lead PV strategy for complex products in different stages of development through input and delivery of safety documents and regulatory reports.
Your duties and responsibilities are likely to include:
Provide subject matter expertise in the therapeutic area and across multiple products
Lead the strategy for proactive PV and risk management planning of complex or multiple products, including preparation of the safety aspects of Global Risk Management Plans and Risk Evaluation and Mitigation Strategies (REMS) in partnership with the Global Safety Physician and others as required.
Lead cross-functional process improvement or other initiatives on behalf of the Patient Safety organisation.
Perform duties as Safety Strategy and Management Team Leader for complex and/or multiple products.
Lead presentation of intricate issues to Safety Information Review Committee.
Lead safety strategy for multiple or complex periodic regulatory documents (PBRERs, PSURs, DSURs) according to the agreed process and timelines.
Lead safety strategy for regulatory submissions of new products, formulations or indications (NDA/BLA, MAA) with the GSP and other functional specialists.
Handle negotiations and provide expertise to the PS component of contracts/agreements with third parties to ensure quality and integrity of agreements.
Take accountability and lead resolution of safety issues and mediate cross-functional agreement.
Participate in due diligence activities.
Provide training and mentorship to new GSPs and PV Scientists in approved processes and systems
Essential for the role
A degree in life sciences (or similar field) and advanced Patient Safety and/or Clinical/Drug Development experience
Demonstrated experience in oncology, ideally with radioconjugates.
Excellent written and verbal English
Advanced knowledge of PV regulations
Clinical Development (Early and/or Late Phase)
Post-Marketing surveillance
MAA/BLA Submissions
Periodic Reports
Risk Management Plans (from scratch)
Governance Board Interactions
Desirable for the role
PharmD/MSc/PhD in scientific field
Advanced understanding of epidemiology
Date Posted
12-ago-2026
Closing Date
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Job details
How this role compares
Computed from every other active Pharmacovigilance role in our database, not just this employer's listings.
We currently track 16 comparable Director Pharmacovigilance roles across 11 biopharma companies.
Salary context
3 of 16 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 16 comparable roles
+ 1 more countries
Seniority mix
16 of 16 peers have a known seniority level
Therapeutic area mix
4 of 16 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.