Senior Application Support Engineer – SPE
About this opportunity
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work, but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
About the Technology Organization
Technology at Lilly builds and maintains capabilities using pioneering technologies like most prominent tech companies. What differentiates Technology at Lilly is that we create new possibilities through tech to advance our purpose – creating medicines that make life better for people around the world, like data driven drug discovery and connected clinical trials. We hire the best technology professionals from a variety of backgrounds, so they can bring an assortment of knowledge, skills, and diverse thinking to deliver solutions in every area of our business.
About the Business Function
The Software Product Engineering (SPE) team is a specialised engineering group that delivers strategic solutions and differentiated capabilities. We take a forward-thinking approach, focusing on an enterprise platform and product mindset, ensuring that the solutions we build can be leveraged across Technology teams for broader impact and efficiency.
Job Title: Senior Software Engineer – Operations
Role Summary
As a Software Engineer – Operations, you will provide advanced technical support for a suite of products, acting as the escalation point for L2 support and customer queries. You will troubleshoot, diagnose, and resolve incidents related to application functionality, integrations, performance, and security, collaborating closely with development and cross-functional teams to deliver timely fixes and ensure product quality.
What You’ll Be Doing
Provide advanced technical support for suite of products, acting as the escalation point for L2 support and customer queries.
Troubleshoot, diagnose, and resolve incidents related to application functionality, integrations, performance, and security.
Collaborate with development teams (frontend, backend, full stack) to analyse root causes, reproduce issues, and deliver timely fixes or workarounds.
Monitor application health, logs, and alerts using tools such as AWS CloudWatch, Winston, or similar.
Maintain and update knowledge base articles, FAQs, and runbooks for recurring issues and resolutions.
Support deployment activities, including post-release validation and rollback procedures.
Participate in incident management, including RCA (Root Cause Analysis), documentation, and communication with stakeholders.
Ensure compliance with internal standards and external regulations (e.g., GDPR, HIPAA, as relevant).
Contribute to continuous improvement of support processes.
Collaborate cross-functionally with product, QA, and engineering teams to drive product quality and customer satisfaction.
Take responsibility for authoring technical documents, including design documents, runbooks, troubleshooting guides, and other relevant documentation to support operations and knowledge sharing.
How You Will Succeed
Demonstrate strong analytical and problem-solving skills, with hands-on experience in debugging web applications (frontend and backend).
Utilise monitoring, logging, and alerting tools (e.g., AWS CloudWatch, Winston, Datadog, ELK).
Work effectively with ticketing systems (e.g., Jira, ServiceNow) and incident management workflows.
Apply good understanding of RESTful APIs, databases (PostgreSQL, Redis), and cloud platforms (AWS, Azure, GCP).
Support CI/CD pipelines and deployment processes.
Use basic scripting skills (e.g., Bash, Python, JavaScript) for automation and troubleshooting.
Communicate and collaborate effectively across teams.
What You Should Bring
4–6 years’ experience in application support, technical troubleshooting, or software engineering.
Experience supporting products in regulated industries (Life Sciences, Healthcare, etc.).
Familiarity with frontend frameworks (React, Material-UI) and backend technologies (Node.js, Express.js).
Knowledge of security best practices and compliance requirements.
Exposure to Agile methodologies and SDLC.
Experience with knowledge base management and documentation.
Interest in continuous learning and process improvement.
Bachelor’s degree in computer science, Engineering, or related field (or equivalent practical experience).
Additional Information
Availability to work flexible work hours is/may be required . This team will support continuous operations across two shifts and therefore, this role will require non-standard work hours, and some work on weekends and holidays . Appropriate adjustments in benefits will be provided for employees working non-standard hours where applicable
Candidates should be willing to work on different shifts - 6AM to 2PM or 2PM to 11PM
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
#WeAreLilly
Job details
How this role compares
Computed from every other active Information Technology role in our database, not just this employer's listings.
We currently track 378 comparable Senior Information Technology roles across 34 biopharma companies.
Salary context
45 of 378 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 378 comparable roles
+ 15 more countries
Seniority mix
378 of 378 peers have a known seniority level
Therapeutic area mix
0 of 378 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
No peers with a known therapeutic area yet.
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.