Amgen Inc. Posted June 22, 2026

Postdoctoral Fellow-Discovery Protein Science

South San Francisco, United States Full time
Drug Discovery & Preclinical Research Intern/Fellow/Postdoc

Amgen Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Postdoctoral

Job Description

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Postdoctoral Fellow-Discovery Protein Science

What you will do

Let’s do this! Let’s change the world.

The integrative Protein Generation and Protein Design groups within Discovery Protein Science are seeking a highly motivated and creative scientist to develop impactful platforms toward advancing new therapeutic hypotheses.  In this vital role, you will apply interdisciplinary approaches to develop methodologies for autoantigen profiling, with implications for target identification and biomarker discovery.

This is a 4-year fellowship within Amgen’s Research & Development Postdoc Program, which is dedicated to training the next generation of biomedical scientists.  This is an onsite laboratory position at our South San Francisco site.  To support your research, you will have access to state-of-the art molecular biology, protein design, protein expression, protein biochemistry, and flow cytometry capabilities.

Responsibilities:

As a Postdoctoral Fellow, you will:

Construct and validate protein libraries for autoantigen profiling

Apply generated libraries to profile the binding of complex mixtures of antibodies

Interact and collaborate with scientists cross-functionally, gaining broad exposure to the process of drug discovery

Make novel discoveries that contribute to the broader field, disseminating scientific contributions through impactful publications and conference presentations

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Postdoctoral Fellow we seek is a professional with these qualifications.

Basic qualifications

PhD at the time of appointment in molecular biology, chemical biology, biochemistry, or related life sciences disciplines

Preferred qualifications

Demonstration of independent design, execution, and interpretation of experiments and results, as exemplified by a solid publication record with first-author publication(s)

Proven experience in sequence and structure-based construct design to improve protein expression and high-efficiency cloning methods

Experience with protein library construction, mammalian cell culture, flow cytometry, and NGS analysis workflows is a plus

Excellent critical thinking, organizational, and communication skills

Passion to learn and work collaboratively within a large team of scientists with diverse technical and cultural backgrounds

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is $100,000.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Salary Range

85,238.00USD -115,322.00 USD

Job details

Seniority
Intern/Fellow/Postdoc
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
South San Francisco, United States
Employment type
Full time

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 56 comparable Intern/Fellow/Postdoc Drug Discovery & Preclinical Research roles across 17 biopharma companies.

56Comparable roles tracked
55Currently active
17Companies hiring similar roles
6Countries represented

Salary context

18 of 56 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Associate Scientist I/II, In Vivo Pharmacology · AbbVie $58,656/yr – $99,000/yr
Highest disclosed · Advisor – In Vivo CAR Discovery · Lilly $138,000/yr – $224,400/yr
Peer group range $78,828 – $181,200 (median $90,600)

Where these roles are based

Top locations among the 56 comparable roles

United States49
Germany3
Netherlands1
Switzerland1
India1
Canada1

Seniority mix

56 of 56 peers have a known seniority level

Intern/Fellow/Postdoc33
Associate23

Therapeutic area mix

9 of 56 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Neuroscience3
Oncology2
Cardiovascular / CVRM2
Immunology1
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Lilly Indianapolis, Indiana, United States of America Intern/Fellow/Postdoc
Same function Same seniority Same country
60%similar
Lilly San Diego, California, United States of America Intern/Fellow/Postdoc
Same function Same seniority Same country
60%similar
Lilly Indianapolis, Indiana, United States of America Intern/Fellow/Postdoc
Same function Same seniority Same country
60%similar
Lilly Boston, Massachusetts, United States of America Intern/Fellow/Postdoc
Same function Same seniority Same country
60%similar
Lilly Boulder, Colorado, United States of America Intern/Fellow/Postdoc
Same function Same seniority Same country
60%similar
Lilly Indianapolis, Indiana, United States of America Intern/Fellow/Postdoc
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Postdoctoral Researcher in Translational Oncology
Lilly · Indianapolis, Indiana, United States of America · Intern/Fellow/Postdoc
Function Therapeutic area Seniority Country
60%
QSP postdoctoral scientist
Lilly · Boston, Massachusetts, United States of America · Intern/Fellow/Postdoc
Function Therapeutic area Seniority Country
60%
Post-Doctoral Scientist- Immunology Discovery
Lilly · San Diego, California, United States of America · Intern/Fellow/Postdoc
Function Therapeutic area Seniority Country
60%
Postdoctoral Scientist, Biophysics
Lilly · Indianapolis, Indiana, United States of America · Intern/Fellow/Postdoc
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.