Vertex Pharmaceuticals Inc (US) Posted July 30, 2026

Health Economics & Outcomes Research Associate Director, Pain

Boston, United States Full time
Medical Affairs Associate Director

Vertex Pharmaceuticals Inc (US) is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

Job Description

General Summary:

The Health Economics & Outcomes Research Associate Director will participate in leading the development and execution of Health economics and outcomes research studies in support of Vertex's products. This position reports to the Director, HEOR Pain.

Key Duties and Responsibilities:

Leads others to execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value

Gathers and synthesizes insights from Payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise to strategy planning

Applies best practices to provide key input to the design of Vertex observational research studies

Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact

Partners and works closely with Global Pricing and Market Access to support production of GVD and Value Narrative

Knowledge and Skills:

Strong track record of publication in peer-reviewed journals

Provides technical expertise in HEOR and is able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices

Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences

Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies

Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct

Education and Experience:

Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline.

Typically requires 8 years of experience, with substantial background in HEOR, or the equivalent combination of education and experience

Pay Range:

$176,000 - $264,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1.    Hybrid: work remotely up to two days per week; or select

2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Associate Director
Function
Medical Affairs
Therapeutic area
Not listed
Location
Boston, United States
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 284 comparable Associate Director Medical Affairs roles across 83 biopharma companies.

284Comparable roles tracked
273Currently active
83Companies hiring similar roles
34Countries represented

Salary context

55 of 284 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $176,000/yr – $264,000/yr
Lowest disclosed · Manager, Medical Operations · Merck KGaA $92,900/yr – $139,300/yr
Peer group range $116,100 – $231,700 (median $180,500)

Where these roles are based

Top locations among the 284 comparable roles

United States97
Japan27
Germany24
China22
India22
Taiwan14

+ 28 more countries

Seniority mix

284 of 284 peers have a known seniority level

Manager130
Senior110
Associate Director44

Therapeutic area mix

99 of 284 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology45
Immunology11
Rare Disease11
Dermatology & Aesthetics8
Neuroscience7
Cardiovascular / CVRM7
Vaccines & Infectious Disease6
Respiratory2
Ophthalmology1
Gastroenterology1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.