AbbVie Posted September 1, 2026

Scientist II, In Vivo Pharmacology

North Chicago, IL Full-time
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AbbVie is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  www.abbvie.com . Follow @abbvie on  LinkedIn,   Facebook ,  Instagram ,  X  and  YouTube.

Job Description

Our expanding In Vivo Tumor Biology group in Lake County, IL is hiring a motivated tumor biologist dedicated to discovering and developing innovative small-molecule and biologic therapeutics. The position will focus on tumor-targeting biologics including ADCs and T-cell engager (TCE) therapeutics in both immunocompromised and humanized mouse models. Our scientists collaborate with in vitro biology, translational/biomarker, and medicinal chemistry teams to advance oncology agents through the R&D pipeline. The position is within a dynamic, collaborative research team passionate about advancing novel science and improving patients' lives

The successful candidate will have expertise in designing and executing studies using tumor models in both immunocompromised and immunocompetent mice. Excellent communication skills and a willingness to work with a multidisciplinary team of researchers are essential.

Strong candidates have experience in ADC and TCE therapeutics and familiarity with humanized mouse studies.

Core Responsibilities:

Independently execute, monitor, and interpret in vivo mouse cancer studies (e.g. CDX, PDX, disseminated, syngeneic)

Evaluate novel cancer therapeutics in vivo through efficacy, PK, and tolerability studies.

Collect and prepare tissue from in vivo tumor studies for PD analysis in downstream applications, including IHC, flow cytometry, and RNAseq

Identify, validate and utilize humanized mouse models to support Abbvie pipeline assets.

Interpret results and draw conclusions from own multistage experiments and suggest, design, and pursue relevant experiments that further project goals.

Perform routine and complex tasks competently and independently. May innovate new experimental protocols/techniques.

Appetite for developing novel in vivo approaches and models to address complex biological questions.

Qualifications

BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.

Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions.

Demonstrated ability to learn, understand and master new experimental techniques.

Ability to multitask and work within timelines.

Demonstrated scientific writing skills and strong verbal communication skills.

Key Leadership Competencies

Builds strong relationships with peers and cross-functionally with partners outside the team to enable higher performance.

Learns quickly and changes course when indicated.

Raises the bar and is never satisfied with the status quo.

Embraces others' ideas, nurtures innovation and brings it to reality.

Additional Information

​Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit  https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Job details

Seniority
Not listed
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
North Chicago, IL
Employment type
Full-time

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 449 comparable Drug Discovery & Preclinical Research roles across 59 biopharma companies.

449Comparable roles tracked
427Currently active
59Companies hiring similar roles
20Countries represented

Salary context

171 of 449 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject $84,500/yr – $162,000/yr
Highest disclosed · Executive Director, Biotherapeutics DMPK · Vertex Pharmaceuticals Inc (US) $268,000/yr – $402,000/yr
Peer group range $0 – $335,000 (median $175,000)

Where these roles are based

Top locations among the 449 comparable roles

United States348
Germany16
India13
Switzerland11
United Kingdom11
Canada11

+ 14 more countries

Seniority mix

361 of 449 peers have a known seniority level

Senior113
Principal79
Intern/Fellow/Postdoc46
Director39
Associate Director26
Associate20
Senior Director19
Executive/VP12
Manager7

Therapeutic area mix

68 of 449 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology37
Cardiovascular / CVRM10
Neuroscience8
Immunology6
Respiratory3
Vaccines & Infectious Disease2
Ophthalmology1
Gastroenterology1

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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