Sr. Technical Program Manager, AI Security

The Role:

Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.

Here’s What You’ll Do

Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting

Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process

Build processes, templates, and structure, or leverage existing ones as appropriate

Manage vendors, schedule, scope, and cost

Measure program success (or lack thereof) and risks using data and facts

Provide balanced risk remediation strategies and recommendations and drive risk mitigation

Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna

Provide clear, accurate, consistent, and timely communications

Advance good infrastructure and security practices and culture

Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner

Manage multiple initiatives to oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment, including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production.

Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape role‑based learning paths for AI builders

Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes

Here’s What You’ll Need (Basic Qualifications)

8+ years of Technical Program Management or Engineering Program Management in Artificial Intelligence (AI) / Machine Learning (ML) heavy environments is required

Here’s What You’ll Bring to the Table (Preferred Qualifications)

Background in software engineering, data science, or machine learning

Experience with LLM platforms, prompt engineering workflows, or AI copilots

Experience with AI development platforms, copilots, developer tooling, or MLOps concepts

Experience with responsible AI, model governance, or compliance frameworks

Experience driving structured, process-driven AI transformation initiatives.

Familiarity with tools such as Kubernetes, Airflow, MLFlow, or similar MLOps stacks

Familiarity with governed enablement models (e.g., citizen development, platform standards, golden paths)

Knowledge of security and compliance standards relevant to AI and AI-assisted engineering.

Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders

Embrace a culture of continuous service improvement and service excellence

A desire to make an impact as part of a high-growth, transformational company

Experience with GxP environments and regulatory requirements

Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs, MLOps, data pipelines, and cloud infrastructure

Strong understanding of AI/ML development workflows, AI‑assisted engineering tools, or modern software development platforms

Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills

Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations

Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion

Experience improving developer productivity and building internal tools/platforms.

Ability to define metrics, analyze tradeoffs, and drive decisions with data.

Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback

Proven ability to operate in highly matrixed environments and influence without direct authority.

Excellent written and verbal communication skills, including executive‑level storytelling

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you, at work, at home, and everywhere in between.

Competitive healthcare, plus voluntary benefit programs to support your unique needs

A holistic approach to well-being, with access to fitness, mindfulness, and mental health support

Family planning benefits, including fertility, adoption, and surrogacy support

Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

Savings and investments to help you plan for the future

Location-specific perks and extras

The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Our Working Model 

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.  Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com .

Export Control Notice
This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.
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