Lilly Posted July 28, 2026

Sr Principal Engineer - HSE Global Facilities Delivery

Huntsville, Alabama, United States of America FULL_TIME
Manufacturing & CMC Principal

Lilly is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work, but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Organization Overview:

The Global Facilities Delivery (GFD) Organization delivers new and renovated capital assets around the world.   Our mission is accomplished through a highly leveraged organization of design, construction and qualification contractors.

Responsibilities:

This role will support a new manufacturing site in Huntsville, AL that will supply existing or new medicines for our patients.   When the construction and C&Q is completed, this role will transition to a site HSE operations role to support the manufacture of medicine.

Key Objectives/Deliverables:

Support the management of GFD’s Contractor Safety Management Program (CSMP):

GFD’s Safety Manage and / or own relationship with leveraged Safety Advisor(s) or strategic partners.

Serve as the Subject Matter Expert (SME) for department HSE documents and standards.

Coach GFD’s project teams in complying with GFD’s CSMP.

Project Safety Orientation expectations aligned with compliance standards and industry trends.

Environmental requirements and permits in conjunction with local regulations.

Field confirmation of each project’s application of GFD’s CSMP.

Training for GFD personnel on GFD’s CSMP.

GFD’s Safety processes for Hazard Recognition and Risk Assessment, Confined Space Entry (CSE), Hot Work Permit (HWP), Lock Out/Tag Out (LOTO), Safe To Operate Permit (STOP), etc.

HSE Project Field execution inspections against regulatory, corporate and GFD HSE standards.

Leading and lagging Indicators as well as develop analytics for the project.

Work closely with Global HSE and GFD HSE SMEs to ensure alignment with corporate priorities and standards as well as GFD requirements.

Lead, support and/or influence the investigation and Root Cause Analysis (RCA) of unplanned, adverse incidents.

Apply technical skills at a network / global level by demonstrate high degree of influence.

Basic Requirements:

Bachelor’s degree in Safety, Engineering, Environmental Science, Industrial Hygiene, or related technical field.

Minimum (5) years of HSE experience, Experience in 29 CFR 1926 governing construction with no less than 5 years of experience in delivering capital projects.

Direct experience supporting contractor safety management programs and/or permit-to-work (PTW) systems.

Experience working with OSHA regulations, risk management practices, and safe work permitting requirements.

Demonstrated ability to translate regulatory requirements and company standards into practical, field-executable procedures.

Experience supporting contractor lifecycle processes (prequalification, onboarding, field oversight, performance evaluation).

Physically capable of navigating diverse construction environments, including bending, kneeling, climbing ladders, and lifting up to 25 pounds unassisted.

Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Additional Skills/Preferences:

Demonstrates professional excellence through sound independent judgment, strong initiative, and an unwavering commitment to ethical standards.

Proven ability to influence Project Managers and Contractors without direct authority.

Strong written and verbal communication skills.

Exceptional interpersonal skills with a demonstrated ability to inspire and motivate others.

Demonstrated ability to provide technical guidance and field support for HSE programs in operational environments.

Drives results through people, building alignment, accountability, and momentum across teams

Proactively identifies and resolves issues, anticipates scope changes, and ensures safe implementation throughout.

Resolves complex challenges by drawing on deep technical expertise and broad industry knowledge.

Exercises sound judgment and make confident decisions independently, while keeping leadership informed and engaged on matters of critical importance.

Stays current on evolving regulatory and compliance requirements, translating new developments into meaningful process improvements across GFD business operations.

Communicates effectively across all levels, both in writing and in person.

Experience conducting field audits, permit reviews, and contractor observations.

Skilled at influencing stakeholders and organizations outside of direct reporting lines.

Experience in greenfield, major capital project delivery, or startup environments, including construction and commissioning phases.

Experience developing or administering permit-to-work systems.

Familiarity with process safety program integration (MOC, energy isolation, SIMOPS coordination).

Multiple language skills (eg Spanish, etc). OSHA 30 Hour for Construction training

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$66,000 - $171,600

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

Job details

Seniority
Principal
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Huntsville, Alabama, United States of America
Employment type
FULL_TIME

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 393 comparable Principal Manufacturing & CMC roles across 56 biopharma companies.

393Comparable roles tracked
368Currently active
56Companies hiring similar roles
19Countries represented

Salary context

188 of 393 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $66,000/yr – $171,600/yr
Lowest disclosed · Senior Scientist II – CMC Developmental Sciences · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Director, Global Automation Engineering · AbbVie $182,000/yr – $346,000/yr
Peer group range $0 – $264,000 (median $150,600)

Where these roles are based

Top locations among the 393 comparable roles

United States282
India42
Singapore10
Ireland9
Netherlands7
Switzerland6

+ 13 more countries

Seniority mix

393 of 393 peers have a known seniority level

Senior251
Principal78
Director64

Therapeutic area mix

2 of 393 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Lilly Indianapolis, Indiana, United States of America Principal
Same function Same seniority Same country
60%similar
Lilly Louisville, Colorado, United States of America Principal
Same function Same seniority Same country
60%similar
Lilly Indianapolis, Indiana, United States of America Principal
Same function Same seniority Same country
60%similar
Lilly Watertown, Massachusetts, United States of America Principal
Same function Same seniority Same country
60%similar
Lilly Indianapolis, Indiana, United States of America Principal
Same function Same seniority Same country
60%similar
Lilly Indianapolis, Indiana, United States of America Principal
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior/Principal Scientist, Bioprocess Purification Development
Lilly · Indianapolis, Indiana, United States of America · Principal
Function Therapeutic area Seniority Country
60%
Senior Principal Scientist, Analytical Sciences
Lilly · Watertown, Massachusetts, United States of America · Principal
Function Therapeutic area Seniority Country
60%
Sr. Principal or Engineering Advisor - Agentic Lab Automation Integration
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Function Therapeutic area Seniority Country
60%
Principal Scientist, Downstream Process Development
Merck · Rahway, New Jersey, United States of America · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.