Vertex US Distribution Posted June 16, 2026

Senior Medical Science Liaison (Nephrology) - Lower Manhattan, Brooklyn, Staten Island, Long Island

Field Based, United States Full time
Medical Affairs Senior

Vertex US Distribution is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

General Summary:

The Senior Medical Science Liaison (Sr MSL) (Nephrology) for Vertex's broad Nephrology programs including IgAN and AMKD.

The Sr MSL will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources and provide the latest emerging data in response to specific inquiries, as appropriate.

Key Duties and Responsibilities:

Develops and fosters effective and trusting relationships with Thought Leaders (TL) and identifies and engages other appropriate HCPs resulting in scientific engagement with a large network of Nephrology opinion leaders. Additionally, understands the inter-relationships both within and between academic centers and utilizes this expertise to enhance Thought Leader and HCP engagements

Consistently incorporates all aspects of the SEM (Scientific Engagement Model) into all interactions, enhancing the quality of interactions and overall relationships as assessed by field coaching observations

Independently incorporates the medical plan into interactions and territory planning (i.e. listening priorities) and captures valuable feedback in the CRM system to inform internal stakeholders and assist in shaping the medical strategy

Possesses an in-depth understanding of the utility and functionality of the CRM system/data analytics tools, allowing for the time sensitive capture of interaction details. Uses CRM/Analytics to enhance future TL engagements and manage workload

Discusses scientific information effectively and compliantly with external stakeholders at an advanced level of communication for both disease state and product to external stakeholders as assessed by management coaching and field observations

In-depth conceptual and practical knowledge of payers in the region and possesses an in-depth understanding of the impact of payers on patient care delivery

Assists clinical development/clinical operations by fully understanding IB content and presenting IB material, providing nominations for trial sites as requested, providing end of study data reviews with investigators (as needed)

Represents Vertex at medical congresses by providing scientific session/abstract coverage, booth staffing coverage, routine TL interactions, contributing to the daily and end of congress summaries and may provide logistical guidance through organizing and scheduling abstract/session coverage and preparing and delivering the conference debrief (as needed)

May serve as a mentor or trainer for colleagues with less experience; for example, assisting with new hire MSL onboarding

Conducts all activities in compliance with Vertex policy and procedures and performs all administrative tasks in a timely manner such as CRM entry, vehicle mileage reporting, expense reporting, calendar entries, training assignments, etc.

Knowledge and Skills:

Ability to complete goals within allotted timeframes, and deliver high quality results

Ability to help plan and complete projects in a constantly changing field-based environment

Ability to appraise and comprehend medical and scientific literature

Ability to effectively present clinical/scientific information in a credible manner in varied settings

Good knowledge of assigned geographic territory

In-depth understanding of healthcare regulatory environment

Demonstrated working understanding around the compliance and regulatory frameworks that govern the pharmaceutical industry and conducts compliant interactions with internal and external stakeholders.

In-depth knowledge of payers and unique medical information needs to support access and appropriate use of Vertex medicines

Good knowledge of Health Economics and Outcomes Research

Fluent in English (oral and written)

Education and Experience:

Minimum requirement for advanced biomedical or life sciences degree (ex. Masters, NP, PA)

Requires minimum of 4 years of experience as an MSL supporting Nephrology programs or in other medical affairs roles in the pharma/biotech industry or the equivalent combination of education and experience.

Previous training or experience in designated therapeutic area is helpful

Pay Range:

$171,300 - $256,900

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Senior
Function
Medical Affairs
Therapeutic area
Not listed
Location
Field Based, United States
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 160 comparable Senior Medical Affairs roles across 52 biopharma companies.

160Comparable roles tracked
152Currently active
52Companies hiring similar roles
22Countries represented

Salary context

42 of 160 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $171,300/yr – $256,900/yr
Peer group range $144,000 – $231,700 (median $195,125)

Where these roles are based

Top locations among the 160 comparable roles

United States82
India13
Taiwan11
China10
Japan9
Germany6

+ 16 more countries

Seniority mix

160 of 160 peers have a known seniority level

Senior109
Associate Director45
Principal6

Therapeutic area mix

61 of 160 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology26
Rare Disease9
Neuroscience7
Dermatology & Aesthetics6
Cardiovascular / CVRM5
Vaccines & Infectious Disease4
Immunology3
Ophthalmology1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
MSL/Sr. MSL, Psychiatry (Boston, MA)
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Function Therapeutic area Seniority Country
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Senior MSL l- Aesthetics Portfolio
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Senior MSL I – Aesthetics Portfolio
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Senior MSL I – Aesthetics Portfolio
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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.