Vertex Pharmaceuticals Inc (US) Posted June 16, 2026

Senior Director, US Public Policy and Reimbursement

Washington, United States Full time
Medical Affairs Senior Director

Vertex Pharmaceuticals Inc (US) is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

General Summary:

Vertex is seeking a highly experienced and strategic Senior Director, US Public Policy and Reimbursement to lead the development and execution of Vertex’s US Public Policy strategy on policy issues related to access to innovative medicines, with a primary focus on Medicare, Medicaid and related issues. This role will serve as a primary subject-matter expert, strategic architect, and external-facing leader within the U.S. Public Policy and Reimbursement team, working to advance favorable public policies that are both aligned with enterprise goals and support product specific reimbursement strategies amid a rapidly evolving legislative, regulatory, and litigation landscape. The Senior Director will be responsible for collaborating closely with our internals teams to understand key barriers and issues affecting our brands, portfolios and business at the State and Federal level; developing and executing strategies that align with Vertex’s core business objectives and ensure patient access to our innovative medicines; and engaging with the Centers for Medicare & Medicaid Services (CMS) and other relevant federal departments and agencies, policy stakeholders, trade associations, and industry peers to advance Vertex’s priorities. The role will not only monitor and analyze policy developments but proactively shape the external environment, cultivating relationships with key policymakers and stakeholders as well as positioning Vertex as a credible and constructive voice in policy discussions.

The ideal candidate will have a deep understanding of the US healthcare system, particularly Medicare and Medicaid, and a proven track record of successfully navigating complex policy and reimbursement landscapes.

Key Responsibilities:

Develop and execute comprehensive public policy and reimbursement strategies to support Vertex’s business objectives and optimize, mitigate, or enhance policy changes related to access to innovative medicines.

Serve as the primary point of contact with CMS, advocating for policies that support patient access and align with Vertex’s mission, including through rulemaking cycles and ad hoc opportunities.

Build and maintain strong relationships with key policy stakeholders, including government agencies, trade associations, and industry peers.

Monitor, analyze, and interpret federal healthcare policies, regulations, and legislative developments, providing strategic insights and recommendations to internal stakeholders.

Collaborate with cross-functional teams, including Market Access, Legal, and Commercial, to align policy strategies with business priorities, keep them apprised of policy developments, and seek directional input.

Represent Vertex in external forums, including industry coalitions, trade associations, and public policy discussions, to advocate for policies that support innovation and patient access.

Lead the development of policy positions, white papers, and other materials to effectively communicate Vertex’s perspective to policymakers and stakeholders.

Provide strategic guidance to senior leadership on emerging policy trends and their potential impact on Vertex’s business and patients.

Manages certain policy consultants, ensuring that expertise is fully utilized and that deliverables are timely and of high-quality,

Qualifications:

Required Qualifications:

Bachelor’s degree in public policy, health policy, political science, or a related field.

Minimum of 12-15 years of experience in public policy, government affairs, or a related field, with a strong focus on healthcare policy and reimbursement.

Deep knowledge of the US healthcare landscape (especially Medicare and Medicaid), as well as the biopharmaceutical industry, policy/political landscape, reimbursement/access issues, and regulatory and legislative processes.

Proven experience engaging with CMS, trade associations, and other policy stakeholders.

Strong strategic thinking and analytical skills, with the ability to translate complex policy issues into actionable business strategies.

Excellent communication and interpersonal skills, with the ability to build relationships and influence diverse stakeholders.

Preferred Qualifications:

Advanced degree (e.g., JD, MPH, MPP, MBA) is strongly preferred.

Experience working in the biotechnology or pharmaceutical industry.

Demonstrated ability to lead cross-functional teams and manage multiple priorities in a fast-paced environment.

Strong understanding of the broader US healthcare system, including commercial and government payers.

Pay Range:

$248,000 - $372,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1.    Hybrid: work remotely up to two days per week; or select

2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Senior Director
Function
Medical Affairs
Therapeutic area
Not listed
Location
Washington, United States
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 198 comparable Senior Director Medical Affairs roles across 33 biopharma companies.

198Comparable roles tracked
191Currently active
33Companies hiring similar roles
15Countries represented

Salary context

113 of 198 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $248,000/yr – $372,000/yr
Peer group range $205,000 – $458,800 (median $264,000)

Where these roles are based

Top locations among the 198 comparable roles

United States158
China's Mainland8
United Kingdom8
Japan7
Switzerland5
Canada2

+ 9 more countries

Seniority mix

198 of 198 peers have a known seniority level

Director158
Senior Director23
Executive/VP17

Therapeutic area mix

97 of 198 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology37
Immunology16
Respiratory10
Neuroscience9
Cardiovascular / CVRM7
Vaccines & Infectious Disease6
Dermatology & Aesthetics6
Rare Disease5
Ophthalmology1

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.