Lilly Posted June 18, 2026

Process Safety Lead

Indianapolis, Indiana, United States of America FULL_TIME
Manufacturing & CMC

Lilly is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Engineering Technology Center (ETC) is a group of skilled engineering practitioners who possess deep technical expertise.  The primary role of this position is to provide process safety related technical support to manufacturing.   The ETC partners with manufacturing and other engineers across the company to deliver capital projects, address operational issues, and provides solutions to key business problems across the company.

Responsibilities:

This role is the Process Safety Management technical resource in the ETC.

Become a key engineering/technical resource for the GIPSM processes across Lilly such as Mechanical Integrity, Process hazards, Pressure safety, and others.

Be a corporate technical resource on pressure relief hazards. Provide internal capability to calculate or evaluate pressure relief system sizing.

Recommend external resources for evaluation and sizing of emergency pressure relief systems.

Review third party evaluations of pressure relief system design.

Be a corporate technical resource on Mechanical Integrity Provide technical expertise to ensure alignment with recognized engineering practices and Lilly global engineering standards

Understand critical safety system components and design to support LOPA evaluations

Provide inspection expertise with respect to technology and program setup

Support standardization of MI elements within maintenance package development

Support standardization of Asset Integrity & Repair with respect to Operational Readiness Reviews

Become engineering resource on key GPSIM processes such as Process hazards reviews, process hazard evaluations, LOPA, event investigation, etc.

Partner with GHSE on technical solutions for safety related trends and ownership of key GHSE standards and expectations

Partner with LRL colleagues on ensuring process safety related aspects are considered when developing new processes, products.

Adaptability

Flexibility in adapting and adjusting to changes in working practices and willingness to take on different roles as required by the needs of the Engineering Tech Center

Ability to work with diverse perspectives and to identify and resolve issues with minimal direction.

Basic Qualifications:

Bachelor's in Engineering (e.g. Chemical Engineering)

Minimum 8 years' experience in pharmaceutical and/or specialty chemical laboratory and/or manufacturing environments

Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1

Additional Preferences:

Professional engineering license.

Experience as a mechanical or process engineering in two or more of the following areas: small molecule bulk, large molecule bulk, dry products, parenteral products, delivery devices, utilities, facilities management, Lilly Research.

Demonstrated knowledge of US and non-US codes and standards applicable to emergency pressure relief.

Must have demonstrated good written and verbal communications skills. Demonstrated ability to work within and lead diverse, multi-functional teams (i.e. Engineering, Manufacturing Operations leadership, TS/MS, etc.).

Demonstrated project management, interpersonal and communication skills.

Ability to identify and resolve issues with minimal direction.

Demonstrated familiarity with understanding and application of common engineering specifications/standards to identify and resolve issues with minimal direction.

Must be able to work in an environment where limited or conflicting direction is given.

Qualified to perform emergency relief calculations.

Knowledgeable of first principles.

Additional Information: 

ETC supports all business areas across the globe.  Business travel both inside and outside the U.S. may be required.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$66,000 - $171,600

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

Job details

Seniority
Not listed
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Indianapolis, Indiana, United States of America
Employment type
FULL_TIME

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 1527 comparable Manufacturing & CMC roles across 125 biopharma companies.

1527Comparable roles tracked
1434Currently active
125Companies hiring similar roles
44Countries represented

Salary context

455 of 1527 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject $66,000/yr – $171,600/yr
Lowest disclosed · Senior Scientist II – CMC Developmental Sciences · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Peer group range $0 – $540,400 (median $140,000)

Where these roles are based

Top locations among the 1527 comparable roles

United States781
India104
Germany74
Singapore67
France64
Ireland54

+ 38 more countries

Seniority mix

705 of 1527 peers have a known seniority level

Senior251
Manager165
Principal79
Associate68
Director64
Associate Director44
Senior Director21
Intern/Fellow/Postdoc8
Executive/VP5

Therapeutic area mix

7 of 1527 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease6
Oncology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
Alexion New Haven, Connecticut, United States of America
Same function Same country
40%similar
AstraZeneca Cambridge, Massachusetts, United States of America Director
Same function Same country
40%similar
Alexion New Haven, Connecticut, United States of America
Same function Same country
40%similar
40%similar
Lilly Boston, Massachusetts, United States of America Associate
Same function Same country
40%similar
Lilly Indianapolis, Indiana, United States of America Senior Director
Same function Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Scientist II, LC Development, Biologics Analytical Development
Alexion · New Haven, Connecticut, United States of America · Seniority not listed
Function Therapeutic area Seniority Country
40%
Director, Global Regulatory Affairs – Chemistry, Manufacturing and Controls (CMC), Platform Innovation – Synthetic Peptides and Oligonucleotides
Lilly · Indianapolis, Indiana, United States of America · Director
Function Therapeutic area Seniority Country
40%
Senior/Principal Scientist, Bioprocess Purification Development
Lilly · Indianapolis, Indiana, United States of America · Principal
Function Therapeutic area Seniority Country
40%
Senior Principal Scientist - Bioanalytical Research
Lilly · Louisville, Colorado, United States of America · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.