Roche Posted August 20, 2026

Principal GPU Software Engineer

Santa Clara, California, United States of America FULL_TIME
Information Technology Principal

Roche is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Roche Sequencing is not only changing science, but we are changing lives. Our software teams are laying the groundwork for the future by developing powerful bioinformatics algorithms, data analysis tools, and software/systems infrastructures so researchers and clinicians can make better health decisions faster. The path to curing cancer lies in ones and zeros as we work with next-generation genomic sequencing, a new frontier.

Do you want to develop software products that scientists and others in the life sciences will use to diagnose, find treatments, and eventually beat diseases like cancer? Our team builds highly scalable, reliable software and secure systems for better diagnostics. Come join us!

The Opportunity

As a Bioinformatics Software Engineer, you will design and develop automated verification tests for the bioinformatics components and pipelines that are used in Roche Sequencing products. You will be part of the team developing cutting-edge, distributed, scale-out Next-Generation Sequencing data analysis software to ensure the highest possible software quality for gene sequencing research and disease diagnostics.

Work closely with research and algorithm experts, accelerating bioinformatics techniques using GPU hardware. Support software development lifecycle and Design Control process, working closely with team members to continuously improve quality and feature sets of the software products, based on technical design and requirements specificationsWork closely with team members to continuously improve the quality and feature sets of software products. This includes supporting the software development lifecycle and Design Control process, based on technical design and requirements specifications.

Who You Are

B.S. or M.S. or PhD in Software Engineering, Data Science or Computational Biology or related field.

5+ years of experience in working in Object-Oriented Programming (OOP) using C++ and practical experience utilizing GPU-accelerated C/C++ libraries.

Strong expertise in Python, including numerical computing and data science libraries.

Experience with CI/CD tools and concepts.

Experience designing, documenting and executing verification tests.

Be self-driven, detail oriented, analytical and proven ability to learn quickly.

Be a team player, customer focused with excellent interdisciplinary collaboration skills.

Preferred Qualifications

NGS data and bioinformatics pipeline verification.

Proficiency in AWS and Linux Shell environments

Software verification experience focusing on medical device software or regulated applications.

Relocation benefits are not available for this posting

The expected salary range for this position based on the primary location of California is $165,800 - $308,000 annual.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

 

 

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .

Job details

Seniority
Principal
Function
Information Technology
Therapeutic area
Not listed
Location
Santa Clara, California, United States of America
Employment type
FULL_TIME

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 412 comparable Principal Information Technology roles across 41 biopharma companies.

412Comparable roles tracked
379Currently active
41Companies hiring similar roles
21Countries represented

Salary context

51 of 412 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Senior Data Security Engineer (Insider Risk Management – Engineering) · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Director, Product Management · $223,642/yr – $305,200/yr
Peer group range $0 – $264,421 (median $155,400)

Where these roles are based

Top locations among the 412 comparable roles

India216
United States90
Spain19
Poland15
Portugal11
Greece11

+ 15 more countries

Seniority mix

412 of 412 peers have a known seniority level

Senior322
Principal54
Director36

Therapeutic area mix

2 of 412 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Roche Santa Clara, California, United States of America Principal
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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Function Therapeutic area Seniority Country
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Principal Automation Systems Administrator, Manufacturing & Lab Support
Regeneron Pharmaceuticals, Inc (USA) · Renss, United States · Principal
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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.