Lilly Posted June 18, 2026

Principal - Engineer – Automation (Building Management Systems)

Houston, Texas, United States of America FULL_TIME
Manufacturing & CMC Principal

Lilly is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly is currently constructing an advanced manufacturing facility for production of API molecules located in Houston, TX.  This facility is intended to provide APIs for current and future products, including new modalities.  This is a unique opportunity to be a part of the site technical team for the startup of a greenfield manufacturing site, and the successful candidate will help to build the organization, the facility and the culture to enable a successful startup into GMP manufacturing operations.

Responsibilities:

The Principal Automation Engineer – Building Management Systems is a mid-level automation engineering position that will support the design and delivery of the automation platforms and associated system integration as part of Lilly’s manufacturing expansion. This role is intended to support manufacturing and admin buildings to design and deliver the site Building Management Systems (sometimes referred to as Building Automation Systems).  Key responsibilities include system design, process design, delivery strategy, factory acceptance testing, and installation and system commissioning.  Lilly Houston is part of Lilly’s Drug Substance (Active Pharmaceutical Ingredient) network.

During the design and delivery (startup expected 2029 to 2030) of the project this role will be integrated into the corporate automation team GPACE (Global Process Automation & Control Engineering) and then transition fully to a site-based process team position.  During delivery, this role will collaborate with A&E firms, system integrators, corporate and site engineering peers, and Tech@Lilly (Lilly’s corporate IT team) to develop and manage software/hardware design, testing, startup, commissioning, and qualification.

Post-project delivery, this role will support GMP manufacturing operations in the central engineering function.  This role will require significant collaboration, creativity and resilience as the site grows to a full scale GMP manufacturing site through start up.

Key Deliverables:

Champion a strong safety culture, mentor and coach others, and utilize engineering and automation fundamental principles in design and problem solving.

Collaborate with Lilly Engineering, A&E firms, and system integrators to develop requirements and specifications that will be the foundation for software development, hardware design, and system architecture.

Support the design and delivery, collaborating with Lilly’s A&E and selected Building Management System supplier, of the site BMS platform.

Support the design and delivery of AF&ID’s, P&ID’s, instrument specifications, sequences of operation, panel design, and testing strategies for the BMS platforms.

Collaborate with Tech@Lilly to deliver a fully integrated Automation solution that is scaled for the needs of business if applicable.

Participate in basic and detailed design that also includes staffing, statements of work, supplier management, and delivery strategies for automation systems.

Participate in developing computer system validation strategies.

Develop and build capabilities within the Houston site automation team.

Develop site procedures for automation platforms and associated administration activities.

Provide engineering support for Process Safety Management (PSM) and Process Hazard Reviews (PHRs).

Provide technical oversight during development of equipment and process system User Requirements and related Design Review/Qualification documentation to ensure equipment and systems are appropriate for intended purpose.

Basic Qualifications:

Bachelor’s degree in engineering or related applicable discipline required.

3+ years of experience in Building Management or Building Automation Systems.

3+ years of experience in Process Automation with experience on Rockwell Automation Platforms, JCI Metasys, or Siemens Desigo preferred.  Related control system platforms will be considered.

3+ years of experience in manufacturing.

Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Additional Skills/Preferences:

Technical knowledge in process instrumentation.

Strong analytical and critical thinking skills.

Ability to collaborate with others.

Technical knowledge on the utilization of data historians.

Additional Information:

Potential for travel (less than 20% - could be domestic and/or international) to support system, factory acceptance testing, and training.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$66,000 - $171,600

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

Job details

Seniority
Principal
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Houston, Texas, United States of America
Employment type
FULL_TIME

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 393 comparable Principal Manufacturing & CMC roles across 56 biopharma companies.

393Comparable roles tracked
368Currently active
56Companies hiring similar roles
19Countries represented

Salary context

188 of 393 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $66,000/yr – $171,600/yr
Lowest disclosed · Senior Scientist II – CMC Developmental Sciences · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Director, Global Automation Engineering · AbbVie $182,000/yr – $346,000/yr
Peer group range $0 – $264,000 (median $150,600)

Where these roles are based

Top locations among the 393 comparable roles

United States282
India42
Singapore10
Ireland9
Netherlands7
Switzerland6

+ 13 more countries

Seniority mix

393 of 393 peers have a known seniority level

Senior251
Principal78
Director64

Therapeutic area mix

2 of 393 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Lilly Indianapolis, Indiana, United States of America Principal
Same function Same seniority Same country
60%similar
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60%similar
Lilly Indianapolis, Indiana, United States of America Principal
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60%similar
Lilly Indianapolis, Indiana, United States of America Principal
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60%similar
Lilly Indianapolis, Indiana, United States of America Principal
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior/Principal Scientist, Bioprocess Purification Development
Lilly · Indianapolis, Indiana, United States of America · Principal
Function Therapeutic area Seniority Country
60%
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Merck · Rahway, New Jersey, United States of America · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.