AbbVie Posted July 10, 2026

Principal Agentic AI Security Engineer

North Chicago, IL Full-time
Information Technology Principal

AbbVie is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  www.abbvie.com . Follow @abbvie on  LinkedIn,   Facebook ,  Instagram ,  X  and  YouTube.

Job Description

We are building a team that develops AI agents to solve hard security problems -- and you will be tackling the hardest ones. This is a hands-on, senior IC role. You will architect, build, and ship agentic AI systems that operate autonomously within security environments, while also driving the technical direction and standards for how these systems are built, tested, and secured.

This is not a management role and not a pure research role. You will write code, ship systems, and get your hands dirty -- but you will be working on problems where there is no playbook yet. You will define the approach, build the proof of concept, harden it for production, and write the technical guidance others follow.

Responsibilities:

Architect and build AI agent systems for security operations -- autonomous detection, investigation, response, threat hunting, vulnerability analysis, and risk assessment

Tackle the novel, high-complexity problems: adversarial robustness of agent systems, secure agent-to-agent communication, guardrails for autonomous decision-making in high-stakes security contexts

Develop frameworks, tooling, and patterns for building secure and reliable agentic AI systems -- then use them yourself

Conduct original research and experimentation on agentic AI applied to offensive and defensive security, translating findings into working code

Build proof-of-concept exploits and adversarial tests against agentic AI systems to identify failure modes and inform defensive design

Develop and publish technical guidance and policy for agentic AI security -- grounded in systems you have built and broken

Independently author security position papers on emerging technologies -- strategic, high-level documents that frame organizational thinking on new threat domains and drive downstream policy and technical guidance

Serve as a subject matter expert and key driver of the AI Cybersecurity Maturity program, spanning application security, training, AI controls and infrastructure, AI discovery and inventory, operations and incident response, and policy and procedure development

Integrate LLMs, custom models, and security tooling (SIEM, EDR, SOAR, cloud platforms, vulnerability scanners) into agent architectures

Evaluate and adopt emerging AI capabilities (new models, frameworks, techniques) and determine their applicability to security problems

Set technical direction for agent development practices, including evaluation frameworks, testing methodologies, and deployment patterns

Mentor and elevate other engineers on the team through code review, design guidance, and technical leadership

Qualifications

Required: 

Bachelor's Degree with 9 years’ experience; Master's Degree with 8 years’ experience; PhD with 4 years’ experience.

Respective years of experience in cybersecurity, security engineering, or security research -- with substantial hands-on technical depth

Strong software engineering skills -- you ship production systems, not just prototypes. Python required; additional languages a plus

Deep expertise in at least two of: security operations, application security, threat intelligence, vulnerability research, detection engineering, offensive security, cloud security

Demonstrated experience building AI agents and AI/ML-powered security tools or automation that operated at scale

Hands-on experience with agentic coding tools (e.g., Claude Code, Cursor, GitHub Copilot, Aider, or similar) as part of your daily development workflow -- you build with agents, not just build agents

Track record of original technical work -- published research, open-source tooling, conference presentations, or equivalent evidence of independent technical contribution

Ability to work at the intersection of security and AI: you understand both the security implications of AI systems and how to apply AI to security problems

Experience developing technical standards, frameworks, or guidance that others adopted

Strong written and verbal communication -- you can explain complex technical concepts to both engineers and senior leadership, and you can write strategically about emerging technology risks at a level that shapes organizational direction

Preferred:

Experience with agent orchestration and autonomous systems (custom frameworks, LangChain, AutoGen, MCP, or similar)

Background in adversarial ML, AI red teaming, or AI safety

Familiarity with security compliance frameworks (NIST, ISO 27001, SOX) and how they apply to AI systems

Published work (Black Hat, DEF CON, OWASP, academic journals, or equivalent venues)

Experience in regulated industries (financial services, healthcare, critical infrastructure, government/defense)

Contributions to open-source security projects

OWASP, MITRE ATT&CK, or similar framework expertise applied in production environments

Security clearance eligibility (not required)

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit  https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Job details

Seniority
Principal
Function
Information Technology
Therapeutic area
Not listed
Location
North Chicago, IL
Employment type
Full-time

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 367 comparable Principal Information Technology roles across 36 biopharma companies.

367Comparable roles tracked
343Currently active
36Companies hiring similar roles
20Countries represented

Salary context

45 of 367 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $141,500/yr – $268,500/yr
Lowest disclosed · Senior Data Security Engineer (Insider Risk Management – Engineering) · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Director, Product Management · $223,642/yr – $305,200/yr
Peer group range $0 – $264,421 (median $151,100)

Where these roles are based

Top locations among the 367 comparable roles

India197
United States74
Spain17
Poland14
Portugal11
Greece9

+ 14 more countries

Seniority mix

367 of 367 peers have a known seniority level

Senior290
Principal49
Director28

Therapeutic area mix

1 of 367 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Roche Santa Clara, California, United States of America Principal
Same function Same seniority Same country
60%similar
Regeneron Pharmaceuticals, Inc (USA) Renss, United States Principal
Same function Same seniority Same country
60%similar
Regeneron Genetics Center (USA) Tarrytown, United States Principal
Same function Same seniority Same country
60%similar
Regeneron Pharmaceuticals, Inc (USA) Renss, United States Principal
Same function Same seniority Same country
60%similar
Regeneron Pharmaceuticals, Inc (USA) Warren, United States Principal
Same function Same seniority Same country
60%similar
Regeneron Pharmaceuticals, Inc (USA) Tarrytown, United States Principal
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Principal Software Development Engineer
Roche · Santa Clara, California, United States of America · Principal
Function Therapeutic area Seniority Country
60%
Principal Automation Systems Administrator, Manufacturing & Lab Support
Regeneron Pharmaceuticals, Inc (USA) · Renss, United States · Principal
Function Therapeutic area Seniority Country
60%
Principal Business Analyst - Velocigene
Regeneron Pharmaceuticals, Inc (USA) · Tarrytown, United States · Principal
Function Therapeutic area Seniority Country
60%
Principal Business Analyst – Science Data Portal
Regeneron Pharmaceuticals, Inc (USA) · Tarrytown, United States · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.