Executive Medical Director, Global Medical Lead (Pain)

Job Description

General Summary:

The Executive Medical Director, Global Medical Lead (GML), Pain is a critical leadership role in Global Medical,   responsible for the global medical strategy   and impl eme ntation   and tracking   of   global activities for   a designated   disease area(s) .   Key responsibilities include, but are not limited to,   disease   area   specific   Integrated   Medical Plan development,   including   the   publication plan,   global   launch strategy   and execution, scientific leadership, external medical expert engagement, and strategic   alignment   with commercial and other cross-functional business partners. This leader will also be critical in leading post-approval evidence generation strategy in the disease area. This leader reports directly to the VP, Global   Medical   and is a core member of the Global Medical leadership team.   They will lead the   global medical affairs team for the designated disease area(s ) and   represents   Medical Affairs in all Global strategic   teams   with   D evelopment and Commercial, including the Disease Strategy Team (DST)   to drive cross-functional alignment,   anticipate   future needs, and contribute to   Medical Affairs   and Vertex’s long-term success.

Key Duties and Responsibilities:

Medical Strategy

Lead   the   development,   implementation,   execution, and communication of the   Integrated Medical Plans,   including   but not limited to   medical strategy,   global tactical plan,   publication ,   congress   and   post - approval evidence generation   plan ,   in collaboration with Clinical Development, HEOR, RWE, Medical Writing, and other internal stakeholders across Vertex

Ensure alignment of medical strategy with organizational   objectives   by integrating individual   and disease area team goals   with Vertex and DST priorities,   and the goals of cross-functional partners

Expertly   distills   insights   and actionable outcomes   that   inform   strategy and   drive the greatest impact for Medical Affairs

Establishes and tracks medical KPIs that   demonstrate   impact on business and patient outcomes.

Applies structured problem-solving and root cause analysis to   identify   solutions   and make decisions   that maximize medical and business impact

Able to   identify   what is important and impactful to medical and the wider business ,   prioritize competing demands   a nd communication to key stakeholders

Accountable   for development of the   global   DA budget, management of funds allocation, and associated tracking to ensure alignment with Medical Affairs priorities and   efficient resource allocation

Scientific Excellence

Serve as product and disease area expert and primary contact point for all gl obal   disease area related issues with the external community and internally at Vertex

Able to   lead   development of peer reviewed publications, congress   presentations   and evidence generation to shape clinical practice

Closely follow medical developments within disease area and   disseminate   new information   to transform clinical trends and emerging data into new plans

Lead the development of global scientific communications and materials including materials for global   led   symposia, advisory boards, and training.

Accountable for medical review of assigned brand related con t ent   and global medical content aligned with Vertex SOPs

External Partnerships

Represent Vertex at scientific and medical forums, including medical education forums, scientific societies, patient advocacy groups, and congresses.

Accountable for engaging and cultivating relationships with leading global key thought leaders (TL) to gain greater understanding of the   disease   area, and insights into unmet patient needs

Medical Communication

Tailors   communication   to stakeholder needs, building trust and understanding across diverse audiences.

Deliver external presentations (advisory board meetings, symposia, other medical education meetings) to enhance the medical knowledge of pipeline and marketed products, as   required   and   in accordance with   relevant regulations and procedures

Support disease area training across the company as   required

Responsible for medical interpretation of data (clinical trials, registries, published literature, etc.) for   pipeline therapies and   marketed medicines

Regional   Medical   and Cross Functional   Collaboration

Accountable for go to market model and medical partnership in commercialization   with global cross-functional colleagues. In   absence   of   regions   teams ,   country   go to market mode l   remains   the responsibility of   the GML.

S upport regional Medical Affairs and Medical Excellence teams from   launch   through lifecycle via   timely   delivery of fit-for-purpose training and core materials.

Responsible for driving alignment on medical content/messaging within the organization to ensure maximal   functional   and regional input.

Medical Affairs   leader   on key global cross-functional product and development strategic focused teams ,   including DST and relevant   sub teams

Effectively   represents   and communicates DST priorities to the medical function and proactively communicates and   represents   medical needs to DST

Chair the Global Medical Area Team (GMAT) for the disease   area   and accountable for deliverables

Provide strategic   Medical Affairs   leadership   on relevant commercial teams: Launch Team, and Global brand teams for product

Represent   Medical Affairs in label discussions

Support Access, Patient Advocacy, Policy, and Corporate Communications teams with medical/scientific   expertise   and materials review.

Evidence Generation and Access

Leads strategy,   development   and execution of   Life Cycle Management   in partnership with HEOR , including   Integrated   Evidence Generation plan in close collaboration with   key internal stakeholders

May act as medical monitor for studies falling under the Medical Affairs scope in collaboration with Clinical Development, Real World Evidence, Health Economics and Outcomes Research, and Clinical Operations

Lead oversight and management of ISS programs, and in collaboration with Regional Medical leadership, conduct critical scientific and medical review of ISS protocols

As applicable, lead Managed Access Committee for assets with a Managed Access Program (MAP); may act as a Medical Monitor for MAP

Team/People Management 

Provide strong leadership to   dedicated   disease area   medical   team, inspiring   and empowering   a dedicated medical team ,   and promoting a culture of continuous development.

Accountable for the   r ecruitment, development, management and coaching the   global   medical team

Leverages the capabilities and   expertise   of the team to ensure successful execution of medical plans

Identifies   and addresses team skill gaps, considering how to accelerate internal talent or attract external to meet   needs   of a future-ready organization.

Adheres to   formal   goal-setting ,   talent and performance cycles ensuring   individual development plans (IDPs)   are in place

Navigates ambiguous or rapidly evolving situations, and   coach   the team during periods of uncertainty or change.

Compliance and Pharmacovigilance:

Ensure compliance   of   medical activities a ccording to global and regional   guidelines and   in accordance with   Vertex   Code of Conduct, rules and regulations, company policies, SOPs, GCP and ICH

Ensure self and othe r   medical   colleagues   have the required skills to   identify   and report AEs   appropriately

Contribute to managing external communication when significant safety issues arise, with the wellbeing of patients being the   ultimate goal

Education and Experience:

MD, PhD, PharmD or other advanced life sciences degree require

Typically requires 15 years of experience and 7 years of supervisory/management experience or the equivalent combination of education and experience

6 or more years of relevant leadership experience in medical affairs and/or clinical development, including experience in both Global and Country/Region desired

2 or more years of industry experience in disease area

Pay Range:

$328,000 - $492,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1.    Hybrid: work remotely up to two days per week; or select

2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com