CRA Manager

Are you ready to lead a high-performing team that accelerates pivotal clinical trials and gets transformative medicines to patients faster? As CRA Manager within US Site Management and Monitoring, you will direct a group of Clinical Research Associates to deliver robust site performance, first-time quality, and on-time execution across a dynamic portfolio. Your leadership will ensure we meet the highest scientific and regulatory standards while keeping patient outcomes at the center. You will shape how we deploy monitoring expertise, optimize resources, and strengthen site relationships across multiple indications. In this role, you will translate strategy into action, coaching, removing barriers, and making data-driven decisions that shorten timelines and elevate quality. Can you create clarity amid shifting priorities and bring out the best in a distributed team? If so, this is your opportunity to leave a measurable mark on an ambitious pipeline.

Accountabilities:

People leadership and development: Provide day-to-day line management for a cohort of CRAs, setting clear expectations and delivering ongoing coaching, mentoring, performance reviews, and talent development to build future leaders

Hiring and onboarding: Interview, hire, and train staff on SOPs, policies, and procedures, establishing a strong foundation in ICH/GCP and company practices

Resource and portfolio planning: Evaluate and project resource needs based on the evolving portfolio; allocate CRAs efficiently to maximize site coverage, reduce bottlenecks, and protect milestones

Study delivery and oversight: Ensure adequate, timely, and compliant monitoring, site management, and oversight for assigned CRAs to drive high-quality execution and audit readiness

Cross-functional collaboration: Build close working relationships with other CRA Managers, Clinical Research Managers, and key internal and external stakeholders to align on priorities and resolve issues quickly

Quality coaching and field engagement: Conduct quality visits with each employee CRA twice annually; use insights to enhance monitoring quality, consistency, and risk-based focus

Transparent communication: Keep staff informed on program and policy changes, and priority shifts; cascade information promptly to sustain alignment and pace

Issue escalation and resolution: Stay attuned to workload and efficiency challenges; collaborate with peers and US leadership to escalate and resolve issues so teams stay focused on delivery

Financial stewardship: Review and approve expenses; ensure timely, compliant expense submissions aligned to company policy and budget discipline

Leadership presence and cadence: Lead regular staff meetings and actively participate in management forums to share insights, reinforce strategy, and drive continuous improvement

Strategic initiatives and best practice: Lead special initiatives that improve trial execution, standardize practices, and scale learnings across teams

Site partnerships and capability building: Partner with priority operational sites to strengthen relationships and accelerate study starts and enrollment; contribute to training and mentoring of new Study Delivery Team members

Process optimization and knowledge sharing: Champion more efficient methods and digital tools that enhance monitoring quality, reduce cycle times, and strengthen data integrity.

Essential Skills/Experience:

University degree in related discipline, preferably in life science, or equivalent qualification

8 years of clinical trial experience with at least 4 years of site monitoring

Study leadership and/or line management preferred

Fluent knowledge of spoken and written English

Excellent knowledge of international guidelines ICH/GCP, basic knowledge of GMP/GDP

Good knowledge of relevant local regulations

Good medical knowledge in relevant AZ Therapeutic Areas

Basic understanding of the drug development process

Good understanding of Clinical Study Management including monitoring, study drug handling and data management

Ability to travel is required, approximately 15%.

Desirable Skills/Experience:

Ability to deliver quality according to the requested standards

Ability to work in an environment of remote collaborators

Manages change with a positive approach for self, team and the business

Sees change as an opportunity to improve performance and add value to the business

Ability to look for and champion more efficient and effective methods/processes of delivering quality clinical trials with reduced budget and in less time

Excellent written and verbal communication skills, negotiation, collaboration and interpersonal skills

Good analytical and problem-solving skills

Demonstrates ability to prioritize and manage multiple tasks with conflicting deadlines

Good cultural awareness

Ability to understand the impact of technology on projects and to use and develop computer skills while making appropriate use of systems/software in an e-enabled environment

Team oriented and flexible; ability to respond quickly to shifting demands and opportunities

The annual base pay for this position ranges from $137,937.60 - $206,906.40. Our positions offer eligibility for various incentives, an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Here, curiosity drives decisions and evidence shapes action. You will join a community that unites scientific rigor with advanced technology to turn promising molecules into medicines that can reshape standards of care, particularly in oncology. We bring unexpected teams together to solve hard problems, publish at the highest levels, and invest deeply in research so ideas can move quickly from concept to clinic. You will be trusted to lead, encouraged to question, and supported by colleagues who value kindness alongside ambition, so your leadership has impact on both your team and patients who need new options.

Lead a team that powers faster, higher-quality trials and help bring the next wave of transformative cancer medicines to patients, share your resume and take the next step today!

Date Posted

12-Aug-2026

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.